5-Aroylamino-2-methyl-2H-l,2.4-thiadiazol-3-ones 3 have been synthesized by oxidative cyclization of l-aroyl-5-methyl-2-thiobiurets 2 with hydrogen peroxide in an alkaline solution. The needed l-aroyl-5-methyl-2-thiobiurets 2 have been obtained throug...
5-Aroylamino-2-methyl-2H-l,2.4-thiadiazol-3-ones 3 have been synthesized by oxidative cyclization of l-aroyl-5-methyl-2-thiobiurets 2 with hydrogen peroxide in an alkaline solution. The needed l-aroyl-5-methyl-2-thiobiurets 2 have been obtained through the addition of methylurea to the corresponding aroyl isothio-cyanates.