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      KCI등재 SCOPUS SCIE

      Loss of glucocerebrosidase 1 activity causes lysosomal dysfunction and α-synuclein aggregation

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      https://www.riss.kr/link?id=A101635515

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      참고문헌 (Reference)

      1 Schondorf DC, "iPSC-derived neurons from GBA1-associated Parkinson's disease patients show autophagic defects and impaired calcium homeostasis" 5 : 4028-, 2014

      2 Bahr BA, "The neuropathogenic contributions of lysosomal dysfunction" 83 : 481-489, 2002

      3 Brady RO, "The metabolism of glucocerebrosides. I. purification and properties of a glucocerebroside-cleaving enzyme from spleen tissue" 240 : 39-43, 1965

      4 Rosenbloom B, "The incidence of Parkinsonism in patients with type 1Gaucher disease : data from the ICGG Gaucher Registry" 46 : 95-102, 2011

      5 Hein LK, "Secondary sphingolipid accumulation in a macrophage model of Gaucher disease" 92 : 336-345, 2007

      6 Murphy KE, "Reduced glucocerebrosidase is associated with increased alpha-synuclein in sporadic Parkinson's disease" 137 : 834-848, 2014

      7 Butler D, "Potential compensatory responses through autophagic/lysosomal pathways in neurodegenerative diseases" 2 : 234-237, 2006

      8 Hoehn MM, "Parkinsonism: onset, progression and mortality" 17 : 427-442, 1967

      9 Dauer W, "Parkinson's disease : mechanisms and models" 39 : 889-909, 2003

      10 Jang A, "Non-classical exocytosis of alpha-synuclein is sensitive to folding states and promoted under stress conditions" 113 : 1263-1274, 2010

      1 Schondorf DC, "iPSC-derived neurons from GBA1-associated Parkinson's disease patients show autophagic defects and impaired calcium homeostasis" 5 : 4028-, 2014

      2 Bahr BA, "The neuropathogenic contributions of lysosomal dysfunction" 83 : 481-489, 2002

      3 Brady RO, "The metabolism of glucocerebrosides. I. purification and properties of a glucocerebroside-cleaving enzyme from spleen tissue" 240 : 39-43, 1965

      4 Rosenbloom B, "The incidence of Parkinsonism in patients with type 1Gaucher disease : data from the ICGG Gaucher Registry" 46 : 95-102, 2011

      5 Hein LK, "Secondary sphingolipid accumulation in a macrophage model of Gaucher disease" 92 : 336-345, 2007

      6 Murphy KE, "Reduced glucocerebrosidase is associated with increased alpha-synuclein in sporadic Parkinson's disease" 137 : 834-848, 2014

      7 Butler D, "Potential compensatory responses through autophagic/lysosomal pathways in neurodegenerative diseases" 2 : 234-237, 2006

      8 Hoehn MM, "Parkinsonism: onset, progression and mortality" 17 : 427-442, 1967

      9 Dauer W, "Parkinson's disease : mechanisms and models" 39 : 889-909, 2003

      10 Jang A, "Non-classical exocytosis of alpha-synuclein is sensitive to folding states and promoted under stress conditions" 113 : 1263-1274, 2010

      11 Daher JP, "Neurodegenerative phenotypes in an A53T alpha-synuclein transgenic mouse model are independent of LRRK2" 21 : 2420-2431, 2012

      12 Xu YH, "Multiple pathogenic proteins implicated in neuronopathic Gaucher disease mice" 23 : 3943-3957, 2014

      13 Sidransky E, "Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease" 361 : 1651-1661, 2009

      14 Balducci C, "Lysosomal hydrolases in cerebrospinal fluid from subjects with Parkinson's disease" 22 : 1481-1484, 2007

      15 Lee H-J, "Intravesicular localization and exocytosis of alpha-synuclein and its aggregates" 25 : 6016-6024, 2005

      16 Cabrera-Salazar MA, "Intracerebroventricular delivery of glucocerebrosidase reduces substrates and increases lifespan in a mouse model of neuronopathic Gaucher disease" 225 : 436-444, 2010

      17 Cuervo AM, "Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy" 305 : 1292-1295, 2004

      18 Orvisky E, "Glucosylsphingosine accumulation in tissues from patients with Gaucher disease: correlation with phenotype and genotype" 76 : 262-270, 2002

      19 Yang NY, "Glucocerebrosidase, a new player changing the old rules in Lewy body diseases" 394 : 807-818, 2013

      20 Goker-Alpan O, "Glucocerebrosidase is present in alpha-synuclein inclusions in Lewy body disorders" 120 : 641-649, 2010

      21 Gegg ME, "Glucocerebrosidase deficiency in substantia nigra of parkinson disease brains" 72 : 455-463, 2012

      22 Pankratz N, "Genomewide association study for susceptibility genes contributing to familial Parkinson disease" 124 : 593-605, 2009

      23 Simon-Sanchez J, "Genome-wide association study reveals genetic risk underlying Parkinson's disease" 41 : 1308-1312, 2009

      24 Satake W, "Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease" 41 : 1303-1307, 2009

      25 Edwards TL, "Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease" 74 : 97-109, 2010

      26 Mazzulli JR, "Gaucher disease glucocerebrosidase and alpha-synuclein form a bidirectional pathogenic loop in synucleinopathies" 146 : 37-52, 2011

      27 Hruska KS, "Gaucher disease : mutation and polymorphism spectrum in the glucocerebrosidase gene(GBA)" 29 : 567-583, 2008

      28 Tsuang D, "GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology" 79 : 1944-1950, 2012

      29 Lee H-J, "Formation and removal of alphasynuclein aggregates in cells exposed to mitochondrial inhibitors" 277 : 5411-5417, 2002

      30 Lee HJ, "Enzyme-linked immunosorbent assays for alpha-synuclein with species and multimeric state specificities" 199 : 249-257, 2011

      31 Ron I, "ER retention and degradation as the molecular basis underlying Gaucher disease heterogeneity" 14 : 2387-2398, 2005

      32 Meikle PJ, "Diagnosis of lysosomal storage disorders : evaluation of lysosomeassociated membrane protein LAMP-1 as a diagnostic marker" 43 : 1325-1335, 1997

      33 Lee H-J, "Clearance of alpha-synuclein oligomeric intermediates via the lysosomal degradation pathway" 24 : 1888-1896, 2004

      34 Bendikov-Bar I, "Characterization of the ERAD process of the L444P mutant glucocerebrosidase variant" 46 : 4-10, 2011

      35 Parnetti L, "Cerebrospinal fluid beta-glucocerebrosidase activity is reduced in Dementia with Lewy Bodies" 34 : 484-486, 2009

      36 Sardi SP, "CNS expression of glucocerebrosidase corrects alpha-synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy" 108 : 12101-12106, 2011

      37 이혜진, "Autophagic failure promotes the exocytosis and intercellular transfer of a-synuclein" 생화학분자생물학회 45 (45): 1-9, 2013

      38 Clark LN, "Association of glucocerebrosidase mutations with dementia with lewy bodies" 66 : 578-583, 2009

      39 Atrian S, "An evolutionary and structure-based docking model for glucocerebrosidase-saposin C and glucocerebrosidase-substrate interactions-relevance for Gaucher disease" 70 : 882-891, 2008

      40 Webb JL, "Alpha-Synuclein is degraded by both autophagy and the proteasome" 278 : 25009-25013, 2003

      41 Trinh J, "Advances in the genetics of Parkinson disease" 9 : 445-454, 2013

      42 Lieberman RL, "A guided tour of the structural biology of gaucher disease : acid-beta-glucosidase and saposin C" 2011 : 973231-, 2011

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2023 평가예정 해외DB학술지평가 신청대상 (해외등재 학술지 평가)
      2020-01-01 평가 등재학술지 유지 (해외등재 학술지 평가) KCI등재
      2009-09-21 학회명변경 한글명 : 대한생화학ㆍ분자생물학회 -> 생화학분자생물학회
      영문명 : Korean Society Of Medical Biochemistry And Molecular Biology -> Korean Society Of Biochemistry And Molecular Biology
      KCI등재
      2008-01-01 평가 SCI 등재 (등재유지) KCI등재
      2006-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2004-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2001-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      1998-07-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 3.74 0.23 2.56
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      1.82 1.45 0.555 0.01
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