To minimize the postoperative hemodynamic changes in neonates with transposition of great arteries (TGA) by modifying the circuit and efficiency of traditional modified ultrafiltration (MUF). Ninety‐one patients (<5 kg) underwent arterial switc...
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https://www.riss.kr/link?id=O119696473
Jia Shen ; Wei Wang ; Wei Zhang ; Lei Jiang ; Yin Yu Yang
2019년
-
0886-0440
1540-8191
SCIE;SCOPUS
학술저널
468-473 [※수록면이 p5 이하이면, Review, Columns, Editor's Note, Abstract 등일 경우가 있습니다.]
0
상세조회0
다운로드다국어 초록 (Multilingual Abstract)
To minimize the postoperative hemodynamic changes in neonates with transposition of great arteries (TGA) by modifying the circuit and efficiency of traditional modified ultrafiltration (MUF). Ninety‐one patients (<5 kg) underwent arterial switc...
To minimize the postoperative hemodynamic changes in neonates with transposition of great arteries (TGA) by modifying the circuit and efficiency of traditional modified ultrafiltration (MUF).
Ninety‐one patients (<5 kg) underwent arterial switch operations, which were randomized to a traditional MUF (tMUF) group (N = 38) or a modified MUF (mMUF) group (N = 53). MUF of both the groups lasted for 8 to 12 minutes, during which the near‐infrared spectroscopy was used to monitor cerebral tissue oxygenation parameters.
The cerebral oxygenation was significantly improved after MUF in both groups. The tissue hemoglobin concentration index (THI) was proportional to the total cerebral hemoglobin during MUF. The ascending velocity of THI was faster in the mMUF group. The mean change range in the mMUF group was 0.90 ± 0.44 mM/cm, while that in the tMUF group was 0.51 ± 0.35 mM/cm (P = 0.028). Quantitative changes in the cerebral concentration of oxygenated hemoglobin increased faster in the mMUF group, in which a nadir of low efficacy MUF was not observed. The rising velocity of the tissue oxygenation index was faster in the mMUF group. All mMUF cases had stable hemodynamics during MUF. The tMUF was aborted in two patients because of unstable hemodynamics. At the end of MUF, hematocrit was significantly greater in the mMUF group than in the tMUF group (40.33 ± 5.43% vs 34.41 ± 5.11%; P < 0.01)
The mMUF circuit is more miniaturized and less prime, which leads to more efficient ultrafiltration. It benefits postoperative hemodynamic stability and oxygen delivery in neonates with TGA.
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