골반에 국한된 난소암 처치에서 대동맥 주위 골반 임파선 절재의 유용성

국문 초록 (Abstract)

목적: Only few trials have addressed the value of systematic aortic and pelvic lymphadenectomy in ovarian cancer macroscopically confined to the pelvis. we studied a randomised trial to evaluate the role of systematic lymphadenectomy at primary surgery in patients with ovarian cancer macroscopically confined to the pelvis.
방법: A total of 64 eligible patients with macroscopically intrapelvic ovarian cancer were randomised to systemic lymphadenectomy (41 patients) or Control (23 patients). Primary surgery was aimed at removing the primary tumour and metastatic pelvic implants and included total abdominal hysterectomy, bilateral salpingo-oophorectomy, total omentectomy, random peritoneal biopsy specimens, peritoneal washing and the removal of all macroscopic intra-pelvic tumor.
결과: Both patients in the systematic aortic and pelvic lymphadenectomy group and control group had not positive nodes at histologic examination. Postoperative chemotherapy was delivered in Most of the patients without renal failure patient. At a median follow-up of 67.8 months, five-year progression- free survival was 73.2 and 73.9% (difference 0.7%) and 5-year overall survival was 85.4 and 82.6% (difference 2.8%) respectively for Control and systematic lymphadenectomy.
결론: In this study, no patient showed lymphatic metastasis. Even when recurred, metastatic cancer was not lymphatic. Systematic lymphadenectomy is not necessary based on this finding.