A Case of Subacute Psychosis in a Patient With Germ Cell Tumor

다국어 초록 (Multilingual Abstract)

We report a case of subacute psychotic symptoms in a patient with germ cell tumor (GCT). The 32-year-old male patient showed progressive psychotic symptoms with diagnosis of GCT. His psychotic symptoms included delusions of reference and persecution. Brain magnetic resonance imaging, electroencephalography, and laboratory examinations were performed to evaluate any other causes. The clinical, neuroimaging, and laboratory review in this case suggested that the progressively developed psychotic symptoms that led to chronic deterioration were caused by the GCT. This is the case report in which subacute atypical psychotic symptoms in his thirties could develop from a GCT based on previous basic research findings showing the correlations of psychotic symptoms with GCT although it has the limitation of so early speculation.

참고문헌 (Reference)

1 곽숙영 ; 윤탁 ; 이남영 ; 정인원 ; 김세현, "식욕억제제 Phentermine, Phendimetrazine으로 유발된 정신병적 장애 증례군 연구" 대한생물정신의학회 24 (24): 134-141, 2017

2 윤제연 ; 이정석 ; 강시현 ; 남범우 ; 이승재 ; 이승환 ; 최준호 ; 김찬형 ; 정영철, "‘2019 한국형 조현병 약물치료 지침서’에 따른 조현병에서 동반증상 및 부작용의 치료" 대한조현병학회 22 (22): 21-33, 2019

3 Jiang X, "Surgical resection of pineal epidermoid cyst contributed to relieving schizophrenia symptoms" 113 : 304-307, 2018

4 Vakis AF, "Psychosis-like syndrome associated with intermittent intracranial hypertension caused by a large arachnoid cyst of the left temporal lobe" 20 : 156-159, 2006

5 Moran LV, "Psychosis with methylphenidate or amphetamine in patients with ADHD" 380 : 1128-1138, 2019

6 Bramness JG, "Psychosis induced by amphetamines" 29 : 236-241, 2016

7 Ananth J, "Psychosis associated with thymoma" 172 : 556-558, 1984

8 Amole M, "Psychosis as initial presentation of small cell lung cancer : a case report" 28 : 335-338, 2022

9 Boele FW, "Psychiatric symptoms in glioma patients : from diagnosis to management" 11 : 1413-1420, 2015

10 Malbari F, "Psychiatric manifestations as initial presentation for pediatric CNS germ cell tumors, a case series" 32 : 1359-1362, 2016

11 Madhusoodanan S, "Psychiatric aspects of brain tumors : a review" 5 : 273-285, 2015

12 Huynh G, "Pharmacological management of steroid-induced psychosis : a review of patient cases" 37 : 120-126, 2021

13 Højlund M, "Obstructive hydrocephalus caused by colloid cyst presenting as a schizophrenia-like psychosis" 2018 : 2018

14 Campbell BA, "New onset psychosis in an adolescent during treatment of testicular germ cell tumor" 33 : e125-e126, 2011

15 Hollis C, "Methylphenidate and the risk of psychosis in adolescents and young adults : a population-based cohort study" 6 : 651-658, 2019

16 Gyawali S, "Meningioma and psychiatric symptoms : an individual patient data analysis" 42 : 94-103, 2019

17 Ali S, "Management of psychosis associated with a prolactinoma : case report and review of the literature" 51 : 370-376, 2010

18 Riedinger CB, "Late relapse of nonseminomatous germ cell tumor 24 years later" 122 : 16-18, 2018

19 Sadock BJ, "Kaplan & Sadock’s synopsis of psychiatry: behavioral sciences/clinical psychiatry" Wolters Kluwer 2015

20 Yang P, "Intracranial multiple germ cell tumors : a case report and review of literature" 7 : 9002-9007, 2014

21 Yeste-Velasco M, "Identification of ZDHHC14 as a novel human tumour suppressor gene" 232 : 566-577, 2014

22 Allen KM, "Gonadectomy increases neurogenesis in the male adolescent rhesus macaque hippocampus" 24 : 225-238, 2014

23 Fischer AS, "Cutaneous presentation of a testicular germ cell tumor with seminomatous differentiation" 40 : 153-154, 2018

24 Estronza S, "Chordoid glioma with psychosis : case report" 37 : 174-176, 2018

25 Puangthong U, "Chemotherapy-induced acute psychosis in a patient with malignant germ cell tumour" 2015 : 2015

26 Brown JS Jr, "Cases of remission of psychosis following resection of pheochromocytoma or paraganglioma" 176 : 304-306, 2016

27 Aung T, "Case 1 : acute psychosis in a 16-year-old girl with an ovarian teratoma" 38 : 487-, 2017

28 Dutschke LL, "Brain tumorassociated psychosis and spirituality-a case report" 8 : 237-, 2017

29 Wong CW, "Arachnoid cyst of the lateral ventricle manifesting positional psychosis" 32 : 841-843, 1993

30 Rita CG, "Anti-N-methyl-D-aspartate encephalitis as paraneoplastic manifestation of germ-cells tumours : a cases report and literature review" 2019 : 4762937-, 2019

31 Nugent M, "An adrenal adenoma presenting with psychosis" 47 : 175-177, 2006

32 Magen JG, "Acute lymphocytic leukemia and psychosis : treatment with electroconvulsive therapy" 7 : 133-137, 1995

33 Okumura T, "ACTH-producing thymic neuroendocrine tumor initially presenting as psychosis : a case report and literature review" 10 : 1648-1653, 2019

34 Kuloglu M, "A left temporal lobe arachnoid cyst in a patient with schizophrenia-like psychosis : a case report" 32 : 1353-1354, 2008

35 Schatzberg AF, "A corticosteroid/dopamine hypothesis for psychotic depression and related states" 19 : 57-64, 1985