A New Computerized Diagnostic Algorithm for Quantitative Evaluation of Binocular Misalignment in Patients with Strabismus

다국어 초록 (Multilingual Abstract)

Accurate measurement of binocular misalignment between both eyes is important for proper preoperative management, surgical planning, and postoperative evaluation of patients with strabismus. In this study, we proposed a new computerized diagnostic algorithm that can calculate the angle of binocular eye misalignment photographically by using a dedicated three-dimensional eye model mimicking the structure of the natural human eye. To evaluate the performance of the proposed algorithm, eight healthy volunteers and eight individuals with strabismus were recruited in this study, and the horizontal deviation angle, vertical deviation angle, and angle of eye misalignment were calculated and the angular differences between the healthy and strabismus groups were evaluated using the nonparametric Mann뻎hitney test and the Pearson correlation test. The experimental results demonstrated that there was a statistically significant difference between the healthy and strabismus groups (p = 0.015 < 0.05), but there was no statistically significant difference between the proposed method and the Krimsky test (p = 0.912 > 0.05). The measurements of the two methods were highly correlated (r = 0.969, p <0.05). From the experimental results, we believe that the proposed diagnostic method has a potential to be a diagnostic tool that measures the physical disorder of human eye to diagnose the severity of strabismus non-invasively.

참고문헌 (Reference)

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