일반 상해 및 스포츠 상해로 인한 근·골격계 손상에 대한 모빌리신(Mobilisin®) 효능에 관한 임상연구(Ⅱ) = A Clinical Study of Mobilisin® with Musculoskeletal Injuries

다국어 초록 (Multilingual Abstract)

Mucopolysaccharide polysulfuric ester is definitely absorbed through the skin, and clearly inhibits lysosomal enzymes, so that pain and inflammation are dimimished, simultaneous increase of local blood and lymph flow increases the absorption of exudates and of inflammatory products of metabolism from the tissues. Salicylic acid stabilizes the lysosomal membrane and provents liberation of lysosomal enzyme. Flufenamic acid inhibits the biosynthesis of prostagladins and reduction in the release of lysosomal proteases.
The study was based on the application of Mobilisin(non steroidal anti-inflammatory drug) to 105 patients(athletes=69, general accident=36) with acute musculoskeletal injuries resulting from sports injuries or general accidents. A length of 5-10 cm(Mobilisin) shoud be applied and gently massaged in to the skin several times daily. Results of treatment were assessed taking into account the degree of pain(pain on motion, pain on pressure, spontaneous pain, swelling)to achieve improvement. findings ot the study were as follows:
1. The average disappearance of symptoms after percutaneous application of mucopolysaccharide(Mobilisin®) was as follows: pain on motion in 14 days, pain on pressure in 14 days, spontaneous pain in 7 day, swelling in 7 days
2. The disappearance of symptoms was significantly increased after pre, 3, 7, 14, 21, 28days and maintained through out the entire experimental period. There were significant differences between period(pre-28days.
3. No general side effects reactions were noted.