아시트레틴 투여로 발생한 간질성 폐렴 1예 = A Case of Interstitial Pneumonitis Induced by Acitretin

다국어 초록 (Multilingual Abstract)

Retinoids are effective systemic agents in the treatment of psoriasis. Acitretin, a synthetic aromatic derivative of retinoic acid, has replaced etretinate in retinoid therapy of psoriasis because of its more favorable pharmacokinetic profile, including a significantly shorter half-life. Most of the adverse effects associated with acitretin are teratogenicity, hepatotoxicity, pseudotumor cerebri, pancreatitis, hyperlipidemia, hyperostosis, and mucocutaneous side effects. There are two reports worldwide describing patients who developed acute respiratory distress syndrome associated with acitretin. This suggests the possibility of serious lung complications associated with acitretin. We report a case of a 61-year-old man who developed interstitial pneumonitis that might have been induced by acitretin during the treatment of pustular psoriasis. In these cases, immediate withdrawal of retinoic acid is necessary, and corticosteroid therapy should be considered. (Korean J Med 2011;80:S183-S187)

국문 초록 (Abstract)

저자들은 농포성 건선으로 아시트레틴 투여 후 발생한 간질성 폐렴 환자를 경험하여 문헌고찰과 함께 보고하는 바이다.

참고문헌 (Reference)

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