발달지연을 동반한 다발성 선천성 멜라닌세포 모반 = Multiple Congenital Melanocytic Nevi Associated with Developmental Delay

다국어 초록 (Multilingual Abstract)

Multiple congenital melanocytic nevi (MCMN), defined as the distribution of more than three small- or medium-sized congenital melanocytic nevi (CMN) on the body without a giant CMN, is a rare disease comprising about 4% of patients with CMN. Because MCMN accompanies neurodevelopmental delay, including seizures in 25% of patients as well as the risk of malignant melanoma, it must be carefully followed-up. We report a case of MCMN with developmental delay in a 19-month-old Korean boy. He had a history of febrile seizure when he was 18 months old. He showed a speech delay after the 1-year-follow up, even though there was no evidence of neurocutaneous melanosis (NCM) on brain magnetic resonance imaging (MRI) at the first visit. As MRI has a low sensitivity for detecting NCM in patients with MCMN older than 4-months, close neurodevelopmental assessments should be considered to provide a chance for early rehabilitation. (Korean J Dermatol 2011;49(8):753∼756)