신경근 전기자극의 사전적용이 위축근 기능에 미치는 영향

국문 초록 (Abstract)

본 연구의 목적은 현수 기간 중 적용한 신경근 전기자극의 사전 적용이 흰쥐 뒷다리 근육의 무게와 후지 기능에 미치는 효과를 알아보는데 있다. 이를 위해서 25마리의 Sprague-Dawley계 흰쥐를 14일 동안 현수한 HLS군(n=5)과 14일 동안 자유롭게 사육한 WB군(n=5), 현수 기간 중 14일간 사전 전기자극을 실시한 ES14군(n=5), 현수 기간 중 11일간 사전 전기자극한 ES11군(n=5), 현수 기간 중 7일간 사전 전기자극한 ES7군(n=5)에 무작위 배치하여 실험을 진행하였다. 실험결과, HLS군과 ES7군에서 비복근의 근무게, 후지 활보장의 유의한 감소와 외향각의 유의한 증가가 관찰되었고, ES14군과 ES11군에서 비복근의 근무게와 후지 활보장, 외향각이 유의하게 유지되었음을 관찰하였다. 즉, 14일 및 11일의 사전 신경근 전기자극이 근위축 지연과 근기능 보존에 효과적임을 보여주고 있다. 이러한 결과는 근위축 예방 및 기능 유지를 위해서는 신경근 전기자극을 가능한 조기 적용해야함을 알려주고 있다.

다국어 초록 (Multilingual Abstract)

The purpose of this study was to examine the effect of neuromuscular electrical stimulation(LFES) during hindlimb suspension on weight and function of rat hindlimb muscles. Sprague-Dawley rats(body weight 300-350g) were randomly assigned to five groups: a HLS(n=5) that were hindlimb suspended for 14 days, a WB(n=5) that kept as control, a ES14 that were hind limb suspended for 14days with pre-application of LFES for 14 days, ES11 that were hindlimb suspended for 14 days with pre-application of LFES for 11 days, a LFES 7 that were hindlimb suspended for 14 days with pre-application of LFES for 7 days. Gastrocnemius muscle weight, stride length were significantly decreased and toe out angle were significantly increased in HLS and ES7 groups, whereas muscle weight, stride length, toe out angle were maintained in ES14, ES11. this indicated that LFES for 14 days, LFES for 11 days could prevent muscle atrophy and retain function.

목차 (Table of Contents)

• 요약
• Abstract
• Ⅰ. 서론
• Ⅱ. 재료 및 방법
• Ⅲ. 결과
• Ⅳ. 논의
• Ⅴ. 결론
• 참고문헌
• 저자소개

참고문헌 (Reference)

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