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      New sedatives and analgesic drugs for gastrointestinal endoscopic procedures

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      https://www.riss.kr/link?id=A108288216

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      다국어 초록 (Multilingual Abstract)

      Procedural sedation has become increasingly common in endoscopy. Sedatives and analgesics induce anxiolysis and amnesia. In addi- tion, an appropriate level of sedation is necessary for safe procedures including therapeutic endoscopy. Midazolam and propofol are the most commonly used drugs in sedative endoscopy. In recent years, the need to ascertain the safety and effectiveness of sedation has in- creased in practice. Therefore, new sedatives and analgesic drugs for optimal sedative endoscopy, have recently emerged. This article reviews the characteristics of sedatives and analgesics, and describes their clinical use in gastrointestinal endoscopy.
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      Procedural sedation has become increasingly common in endoscopy. Sedatives and analgesics induce anxiolysis and amnesia. In addi- tion, an appropriate level of sedation is necessary for safe procedures including therapeutic endoscopy. Midazolam and pr...

      Procedural sedation has become increasingly common in endoscopy. Sedatives and analgesics induce anxiolysis and amnesia. In addi- tion, an appropriate level of sedation is necessary for safe procedures including therapeutic endoscopy. Midazolam and propofol are the most commonly used drugs in sedative endoscopy. In recent years, the need to ascertain the safety and effectiveness of sedation has in- creased in practice. Therefore, new sedatives and analgesic drugs for optimal sedative endoscopy, have recently emerged. This article reviews the characteristics of sedatives and analgesics, and describes their clinical use in gastrointestinal endoscopy.

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      참고문헌 (Reference) 논문관계도

      1 Chen YT, "The use of propofol versus dexmedetomidine for patients receiving drug-induced sleep endoscopy : a meta-analysis of randomized controlled trials" 10 : 1585-, 2021

      2 Jalowiecki P, "Sole use of dexmedetomidine has limited utility for conscious sedation during outpatient colonoscopy" 103 : 269-273, 2005

      3 Hall JE, "Sedative, amnestic, and analgesic properties of small-dose dexmedetomidine infusions" 90 : 699-705, 2000

      4 Chen L, "Safety and efficacy of combined use of propofol and etomidate for sedation during gastroscopy: systematic review and meta-analysis" 98 : e15712-, 2019

      5 Scheinin H, "Reversal of the sedative and sympatholytic effects of dexmedetomidine with a specific alpha2-adrenoceptor antagonist atipamezole : a pharmacodynamic and kinetic study in healthy volunteers" 89 : 574-584, 1998

      6 Chen SH, "Remimazolam tosilate in upper gastrointestinal endoscopy : a multicenter, randomized, non-inferiority, phase III trial" 36 : 474-481, 2021

      7 Goudra BG, "Remimazolam : the future of its sedative potential" 8 : 388-991, 2014

      8 Goudra B, "Recent developments in drugs for GI endoscopy sedation" 65 : 2781-2788, 2020

      9 Goudra BG, "Propofol alternatives in gastrointestinal endoscopy anesthesia" 8 : 540-545, 2014

      10 Lee Yoo Min ; Kang Ben ; Kim Yu Bin ; Kim Hyun Jin ; 이경재 ; Lee Yoon ; Choi So Yoon ; Lee Eun Hye ; Yi Dae Yong ; Jang Hyo-Jeong ; Choi You Jin ; Hong Suk Jin ; Kim Ju Young ; Kang Yunkoo ; Kim Soon Chul, "Procedural Sedation for Pediatric Upper Gastrointestinal Endoscopy in Korea" 대한의학회 36 (36): 1-14, 2021

      1 Chen YT, "The use of propofol versus dexmedetomidine for patients receiving drug-induced sleep endoscopy : a meta-analysis of randomized controlled trials" 10 : 1585-, 2021

      2 Jalowiecki P, "Sole use of dexmedetomidine has limited utility for conscious sedation during outpatient colonoscopy" 103 : 269-273, 2005

      3 Hall JE, "Sedative, amnestic, and analgesic properties of small-dose dexmedetomidine infusions" 90 : 699-705, 2000

      4 Chen L, "Safety and efficacy of combined use of propofol and etomidate for sedation during gastroscopy: systematic review and meta-analysis" 98 : e15712-, 2019

      5 Scheinin H, "Reversal of the sedative and sympatholytic effects of dexmedetomidine with a specific alpha2-adrenoceptor antagonist atipamezole : a pharmacodynamic and kinetic study in healthy volunteers" 89 : 574-584, 1998

      6 Chen SH, "Remimazolam tosilate in upper gastrointestinal endoscopy : a multicenter, randomized, non-inferiority, phase III trial" 36 : 474-481, 2021

      7 Goudra BG, "Remimazolam : the future of its sedative potential" 8 : 388-991, 2014

      8 Goudra B, "Recent developments in drugs for GI endoscopy sedation" 65 : 2781-2788, 2020

      9 Goudra BG, "Propofol alternatives in gastrointestinal endoscopy anesthesia" 8 : 540-545, 2014

      10 Lee Yoo Min ; Kang Ben ; Kim Yu Bin ; Kim Hyun Jin ; 이경재 ; Lee Yoon ; Choi So Yoon ; Lee Eun Hye ; Yi Dae Yong ; Jang Hyo-Jeong ; Choi You Jin ; Hong Suk Jin ; Kim Ju Young ; Kang Yunkoo ; Kim Soon Chul, "Procedural Sedation for Pediatric Upper Gastrointestinal Endoscopy in Korea" 대한의학회 36 (36): 1-14, 2021

      11 Liang DY, "Pharmacological characters of oliceridine, a μ-opioid receptor G-protein-biased ligand in mice" 129 : 1414-1421, 2019

      12 Domino EF, "Pharmacologic effects of CI-581, a new dissociative anesthetic, in man" 6 : 279-291, 1965

      13 Fossler MJ, "Oliceridine(TRV130), a novel G protein-biased ligand at the μ-opioid receptor, demonstrates a predictable relationship between plasma concentrations and pain relief. I : development of a pharmacokinetic/pharmacodynamic model" 58 : 750-761, 2018

      14 Eskander AE, "Ketamine sedation in gastrointestinal endoscopy in children" 4 : 392-396, 2016

      15 Waring JP, "Guidelines for conscious sedation and monitoring during gastrointestinal endoscopy" 58 : 317-322, 2003

      16 Fechner J, "Fospropofol disodium, a water-soluble prodrug of the intravenous anesthetic propofol(2, 6-diisopropylphenol)" 18 : 1565-1571, 2009

      17 Food and Drug Administration (FDA), "FDA approved drug products: Olinvyk (Oliceridine) injection" FDA

      18 Han SJ, "Etomidate sedation for advanced endoscopic procedures" 64 : 144-151, 2019

      19 Zhou X, "Etomidate plus propofol versus propofol alone for sedation during gastroscopy : a randomized prospective clinical trial" 30 : 5108-5116, 2016

      20 Zhu X, "Efficacy and safety of remimazolam in endoscopic sedation-a systematic review and meta-analysis" 8 : 655042-, 2021

      21 Jhuang BJ, "Efficacy and safety of remimazolam for procedural sedation: a meta-analysis of randomized controlled trials with trial sequential analysis" 8 : 641866-, 2021

      22 Lee JM, "Efficacy and safety of etomidate-midazolam for screening colonoscopy in the elderly: a prospective double-blinded randomized controlled study" 97 : e10635-, 2018

      23 Jae Hyun Kim ; 변상환 ; Youn Jung Choi ; Hye Jung Kwon ; Kyoungwon Jung ; Sung Eun Kim ; Moo In Park ; 문원 ; Seun Ja Park, "Efficacy and Safety of Etomidate in Comparison with Propofol or Midazolam as Sedative for Upper Gastrointestinal Endoscopy" 대한소화기내시경학회 53 (53): 555-561, 2020

      24 Belleville JP, "Effects of intravenous dexmedetomidine in humans. I. Sedation, ventilation, and metabolic rate" 77 : 1125-1133, 1992

      25 Nishizawa T, "Dexmedetomidine vs propofol for gastrointestinal endoscopy : a meta-analysis" 5 : 1037-1045, 2017

      26 Zhang F, "Dexmedetomidine versus midazolam for sedation during endoscopy : a meta-analysis" 11 : 2519-2524, 2016

      27 Nishizawa T, "Dexmedetomidine versus midazolam for gastrointestinal endoscopy : a meta-analysis" 27 : 8-15, 2015

      28 Toklu S, "Comparison of etomidate-remifentanil and propofol-remifentanil sedation in patients scheduled for colonoscopy" 26 : 370-376, 2009

      29 Liu W, "Comparison of clinical efficacy and safety between dexmedetomidine and propofol among patients undergoing gastrointestinal endoscopy : a meta-analysis" 49 : 3000605211032786-, 2021

      30 Cohen LB, "Clinical trial : a dose-response study of fospropofol disodium for moderate sedation during colonoscopy" 27 : 597-608, 2008

      31 Forman SA, "Clinical and molecular pharmacology of etomidate" 114 : 695-707, 2011

      32 Kilpatrick GJ, "CNS 7056 : a novel ultra-short-acting benzodiazepine" 107 : 60-66, 2007

      33 Training Committee, "American Society for Gastrointestinal Endoscopy. Training guideline for use of propofol in gastrointestinal endoscopy" 60 : 167-172, 2004

      34 Cohen LB, "AGA institute review of endoscopic sedation" 133 : 675-701, 2007

      35 Singla N, "A randomized, phase IIb study investigating oliceridine(TRV130), a novel μ-receptor G-protein pathway selective(μ-GPS)modulator, for the management of moderate to severe acute pain following abdominoplasty" 10 : 2413-2424, 2017

      36 Mandel JE, "A randomized, controlled, double-blind trial of patient-controlled sedation with propofol/remifentanil versus midazolam/fentanyl for colonoscopy" 106 : 434-439, 2008

      37 Borkett KM, "A phase IIa, randomized, double-blind study of remimazolam(CNS 7056)versus midazolam for sedation in upper gastrointestinal endoscopy" 120 : 771-780, 2015

      38 Conscious Sedation TFT Committee of KSGE, "A guidebook on sedation for gastrointestinal endoscopy" Medbook 2015

      39 Akbulut UE, "A comparison of sedation with midazolam-ketamine versus propofol-fentanyl during endoscopy in children : a randomized trial" 29 : 112-118, 2017

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