특이 IgG 결합활성과 Immunoblotting에 의한 소아와 임신부의 Varicella Zoster Virus감염의 항체 반응 = Antibody REsponses in Varicella Zoster Virus Infection in Children and Pregnant Women by Specific IgG Avidity and Immunoblotting

다국어 초록 (Multilingual Abstract)

The author measured IgG antibody and IgG avidity of Varicella Zoster Virus(VZV) of sera from pregnant women, children and adults who were hospitalized with unrelated disease.
And the VZV avidity index was calculated, and compared with positivity of IgM antibody of the sera.
The sera were immunoblotting and ovserved whether violet band were formed or not.
The results were as follws;
1. The IgG antibody positivities of VZV were 26/30(86.7%) in children, 23/25(92.0%) in pregnant women and 20/25(80.0%) in adult women with unrelated disease by EIA method.
2. The positivity of VZV antibody was shown in 69/80(86.3%), sera was of which mean OD were around 0.230 similarity in general.
3. The IgG avidity indice of VZV were 61.8% in children, 58.1% in pregnant women, and 71.1% in adult women. These high indice seemed suggestive of past infetion and, or recent reactivations.
4. IgG avidity indice of VZV were between 50-70% in 70.0%(7/10)of IgM antibody positives.
5. Immunoblotting method is a procedure rather complicated but demonstrative of violet band which is to be seen by naked eyes.