마유 리포좀제조 및 마유 리포좀이 포함된 화장품의 제형 및 보습효과연구 = The Moisturizing Effect and Formulation Test of the Cosmetics Composed by Horse Oil Liposomes

다국어 초록 (Multilingual Abstract)

Remaining moisturizing effect on the skin is one of the important functions in cosmetics. Moisturecontents of stratum corneum are directly related to the skin roughness and flexibility. Horse oil containsan unsaturated fatty acid up to 65% and known as excellent penetration and skin moisturizing effect,maintaining healthy skin and skin protecting action. The purpose of this study is to determine how to makehorse oil liposomes, cosmetics formulations and moisturizing effect of products. Liposomes pass throughcell membrane because they composed of phospholipid. The researcher made horse oil to liposomes, formore easier skin absorption of effective components. The researcher used soy lecithin, tocopherol andnatural emulsifier to make horse oil liposomes. Liposomes are made various sizes by manufacturing methodand lipid purity. But if the size of liposomes is too small, it is not easy to get to the dermis. Because smallsize of liposomes is almost absorbed to the keratinocytes. For reach to the dermis, the size of liposomes is100-300 nm. This study measured a size and pH of the horse oil liposomes. The researcher gathered datafor cosmetics formulation and moisturizing effects of products made by horse oil liposomes. Interestingly, thepoint of view in moisturizing effects, cosmetics made by horse oil liposomes are arised incredible outcomes. This research showed that the horse oil and horse oil liposomes are possible to use cosmetics.

참고문헌 (Reference)

1 허정록, "화장품학" 광문각 29-, 2009

2 김수미, "화장품학" 정담미디어 13-113, 2011

3 경기열, "화장품 과학 가이드" 광문각 80-82, 2011

4 랑문정, "현대화장품학" 한국학술정보 23-43, 2007

5 김선영, "쿼세틴의 피부 흡수 증진을 위한 세포 침투 펩타이드 부착 리포좀 시스템" 서울과학기술대학교 산업대학원 2012

6 임경희, "에멀젼 변환과 에멀젼 전이" 한국유화학회 21 (21): 267-273, 2004

7 안봉전, "액정상을 이용한 O/W형 에멀젼의 제조 및 제형 안정화에 관한 연구" 한국유화학회 21 (21): 31-36, 2004

8 정상호, "안전성이 향상된 감초기반 홍삼리포좀의 항노화·항염 효능연구" 아주대학교 대학원 2011

9 박건, "아토피 혁명 실용편" 빛나는 나무 2011

10 유창덕, "아토피 피부염 환자에 적용한 글루칸과 세라마이드제제의 유효성 및 안전성에 대한 연구" 30 : 533-541, 2004

11 강익중, "생명고분자 키토산의 나노입자를 이용한 약물전달 효과" 한국공업화학회 16 (16): 790-793, 2005

12 유지연, "리포좀의 특성 및 안정성에 관한 연구" 6 : 74-81, 2001

13 양은진, "리포좀을 이용한 화장품 제형기술과 경피흡수 기전에 관한 고찰" 건국대학교 산업대학원 2003

14 최성규, "낙타유가 함유된 리포좀 제조 및 피부 노화 개선 효과 연구" 대한화장품학회 40 (40): 155-161, 2014

15 光井武夫, "新化粧品學" 南山堂 191-199, 2001

16 Jeun YS, "Studies on the using liposome cosmetics formulation technology" 1 : 15-19, 2005

17 Esposito E, "Nanosystems for skin hydration: a comparative study" 29 : 39-47, 2007

18 Maghraby GEEl, "Liposome and skin: From drug delivery to model membrane" 34 : 203-222, 2008

19 Kim JH, "Liposome" Biochem. Chongseoljip 1988

20 "LIPOSOMES"

21 "KOSE"

22 Choe M, "Incorporation efficiency and stability of antioxidant nutrients entrapped in liposome" 11 : 21-27, 2001

23 Kheadr EE, "Impact of liposome-encapsulated enzyme cocktails on cheddar cheese ripening" 36 : 241-252, 2003

24 André O., "Handbook of Cosmetic Science and Teahology" Marcel Dekker, Inc 205-, 2001

25 Edwards C, "Evaluation of biomechanical properties of human skin" 13 : 375-380, 1995

26 Kasting GB, "Equilibrium water sorption in human stratym corneum" 92 : 1624-1631, 2003

27 "BIOSPECTRUM"