연령관련 황반변성의 실험모델 연구 = To Study the Experimental Model of Age-Related Macular Degeneration (ARMD)

다국어 초록 (Multilingual Abstract)

We investigated the experimental model papers on age-related macular degeneration (ARMD), one of the world's four major blindness diseases, we intend to suggest the future direction for ARMD prevention and treatment. The overall ARMD-related thesis is divided into in vitro model and in vivo model, and the current research and limitations are summarized.
There are various study to investigate the pathogenesis of ARMD and to treat it, there is no clear therapeutic agent that can treat ARMD until now. It suggests that continuous research on the pathogenesis of ARMD is necessary, and it is necessary to discover natural product candidates that can be used for the treatment and prevention of ARMD.

국문 초록 (Abstract)

세계 4대 실명질환 중 하나인 연령관련 황반변성(Age-related Macular Degeneration, ARMD)에 관한 실험모델 논문을 검토하면서, ARMD 예방과 치료를 위해 앞으로 나아가야 할 방향을 제시하고자 한다. ARMD 관련한 전반적인 논문을 세포실험(in vitro)과 동물실험(in vivo)으로 나누어서 점검하고, 현재 진행하고 있는 연구와한계점에 대해서 살펴보았다. ARMD 발병기전을 연구하고 이를 치료하기 위한 다양한 연구가 진행중이지만, 현재까지 ARMD를 치료할 수 있는 명확한 치료제는 존재하지 않는다. ARMD 발병기전에 대한 지속적인 연구가 필요하고, ARMD 치료와 예방을 위해 활용할 수 있는 천연물 후보물질 발굴이 필요하다고 사료된다.

참고문헌 (Reference)

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