RISS 검색 - 국내학술지논문 상세보기

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다국어 초록 (Multilingual Abstract)

Objective: To investigate the change in maternal BMI from before pregnancy to midtrimester in Korean women with gestational diabetes mellitus (GDM) over recent 12 years and to identify the association between weight gain before midtrimester and GDM development in women with normal range of body mass index (BMI).
Methods: We conducted a retrospective analysis of pregnant women diagnosed with GDM among Korean pregnant women who delivered at Severance Hospital from 2008 to 2017 (n=742). The sample period of 12 years was divided into three equal, consecutive 4-year sub-periods. Clinical characteristics including maternal BMI before pregnancy and at midtrimester, gestational weight gain at early and mid-trimester, GDM treatment methods, and delivery outcomes were reviewed.
Results: Third period (from 2014 to 2017) was associated with a higher maternal height (162cm vs. 158cm, P=0.033), lower pre pregnancy BMI (22.6 kg/m2 vs 24.5 kg/m2, P=0.045), and lower midtrimester BMI (24.7 kg/m2 vs 26.9 kg/m2, P=0.048) compared to the first period (from 2006 to 2009). There was no statistical significant difference in the proportion of patients who were treated with insulin, but the incidents of large-for-gestational-age significantly decreased in the last 4 years compared to the first period (4.97% vs. 10.2%, p=0.037). There was no association between excessive early-midtrimester weight gain and LGA. The proportion of GDM pregnant women who had excessive weight gain in the early and midtrimester in last 4 years was increasing but the difference was not statistically significant.
Conclusion: Our study demonstrated that the incidence of GDM in Korean pregnant women with low BMI is increasing. Increased weight gain between early trimester and midtrimester of pregnancy may affect the increased incidence of gestational diabetes, and further research is needed.