난소암 ( 1966∼1983 ; 연세의료원 ) -Ⅰ. 난소암의 임상 및 조직병리학적 분석 - = Ovarian Cancer ( 1966-1983 , YUMC ) - I.A Clinical and Histopathologic Analysis of Ovarian Cancer -

다국어 초록 (Multilingual Abstract)

A clinico-histopathologic study was made on a series of 142 cases of malignant ovarian cancers, which were admitted to the department of obstetrics and Gycecology, Yonsei University Medical Center during the period Jan 1, 1966 to Dec 31, 1983 The results obtained were as follows: 1. According to FIGO classifcation, the patient were classifed as; stage Ⅰ 38.7% stage Ⅱ 5.6%, stage Ⅲ 15.55 and stage IV 40.25 2. According to WHO histopathological classifcation epithelial ovarian tumor was found in 52.85, germ cell tumor in 20.4% metastatic tumor in 18.3% sex cord-stromal tumor in 8.5% 3. Age distribution of ovarian cancer showed the highest frequency in 45-55 years of epithelial ovarian tumor, 20-30 years of germ cell tumor 4. As for the modalities of treatment surgeries only were performed in 34cases surgeries(including biopsies) with adjuvant chemotherapy in 72cases, and surgeries with adjuvant radiotherapy in 25cases 5. Corrdlation between hisological grading and histologic features such as stratif cation nuclear pleomorphism, papillary projection and stromal invasion showed that these histologic features tend to become more severe as the grade developed 6. A three year cumulative survival rate of epithelial ovarian cancer according to histologic grading was 78% in grade Ⅰ, 55% in grade Ⅱ, 32% in grade Ⅲ, 17% in grade Ⅳ, The survival rate of patients was directly related to histologic grading 7. A three year cumulative survival rate of epithelial ovarian cancer 68% in stage Ⅰ, 38% in stage Ⅱ, 23% in stage Ⅲ, 0% in stage IV. Therefore in the treatment of ovarian cancer it is very important to perform adjuvant radiotherapy of chemotherapy according to the prognostic factors and biologic of the cancer