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      Cellular signal transduction in toxicology and pharmacology : data collection, analysis, and interpretation [electronic resource]

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      https://www.riss.kr/link?id=M15495253

      • 저자
      • 발행사항

        Hoboken, NJ : Wiley, 2019

      • 발행연도

        2019

      • 작성언어

        영어

      • 주제어
      • DDC

        571.7/4 판사항(23)

      • ISBN

        9781119060253
        1119060257
        9781119060161
        1119060168

        9781119060208
        1119060206

      • 자료형태

        일반단행본

      • 발행국(도시)

        New Jersey

      • 서명/저자사항

        Cellular signal transduction in toxicology and pharmacology [electronic resource] : data collection, analysis, and interpretation / edited by Jonathan W. Boyd (West Virginia University, Morgantown, WV, US), Richard R. Neubig (Michigan State University, MI, US).

      • 판사항

        First edition

      • 형태사항

        1 online resource

      • 일반주기명

        Includes bibliographical references and index.
        Intro; Title Page; Copyright Page; Contents; List of Contributors; About the Editors; Preface; Chapter 1 Introduction to Cellular Signal Transduction: The Connection Between a Biological System and Its Surroundings; 1.1 Starting Big, but Ending Small; 1.1.1 Key Features of Signal Transduction; 1.2 Responding to Our Environment: Sensory Perception Begins and Ends with Signal Transduction; 1.2.1 Taste (Gustation); 1.2.2 Smell (Olfaction); 1.2.3 Sight (Vision); 1.2.4 Sound (Audition); 1.2.5 Touch (Somatosensation); 1.3 Primary Transport Systems Involved in Signal Transduction
        1.3.1 Ion Channels, Transporters, and Ion Pumps1.3.2 Receptors; 1.3.3 Endocytosis; 1.3.4 Exosomes; 1.4 Key Organelles Involved in Signal Transduction; 1.4.1 Mitochondria; 1.4.2 Endoplasmic Reticulum; 1.4.3 Nucleus; References; Chapter 2 Mechanisms of Cellular Signal Transduction; 2.1 Posttranslational Modifications and Their Roles in Signal Transduction; 2.1.1 Phosphorylation; 2.1.2 Acylation; 2.1.3 Alkylation; 2.1.4 Glycosylation; 2.1.5 Other PTMs; 2.2 Receptors; 2.3 Receptor Signaling Mechanisms; 2.3.1 Basic Principles of Signal Transduction Mechanisms; 2.3.1.1 Selectivity and Recognition
        2.3.1.2 Flexible Modularity2.3.1.3 Molecular Switches; 2.3.1.4 GPCRs and Second Messengers; 2.3.1.5 Amplification; 2.3.1.6 Turn-Off Mechanisms; 2.3.1.7 Localization; 2.3.1.8 Biased Signaling/Functional Selectivity; 2.4 Receptor Tyrosine Kinases; 2.5 Steroid Receptors; 2.6 Reactive Oxygen Species (ROS); 2.7 Summary; References; Chapter 3 From Cellular Mechanisms to Physiological Responses: Functional Signal Integration Across Multiple Biological Levels; 3.1 Introduction; 3.2 Cellular Information Flow: Mechanisms of Cellular Signal Integration and Regulation

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