核分離計數에 依한 Cortisone의 鷄胎器官成長에 미치는 效果에 關한 硏究 = Study on the Effect of Cortisone to the Growth of the Chick Embryo by Counting the Isolated Nuclei from Cells

다국어 초록 (Multilingual Abstract)

Each 0.5㎎ and 2.0㎎ of cortisone acetate were injected to each subdivided group of 8th day and 12th day incubated chick embryo to study the effect of the cortisone on the growth of the chick embryo, expecially the parenchymatous organs such as brain, kidney and liver by counting the isolated nuclei from cells of these organs and the results were obtained as followings.
1) In general, the embryo group injected cortisone at 8th day of incubation were noted a growth suppression in comparison with the embryo group injected cortisone at 12th day of incubation.
2) In the brain, kidney and liver, the embryo group injected cortisone at 8th day of incubation revealed a low nuclear density per unit volume of organs in comparison with the embryo group injected cortisone at 12th day of incubation(P<0.01).
3) In the brain, kidney and liver, the embryo group injected cortisone at 8th day of incubation revealed a decreased total nuclear number in comparison with the embryo group injected cortisone at 12th day of incubation.
4) Though there was no marked change in number of total nuclei in liver and brain depending upon the change of amount of cortisone injected, in general, in the embryo group cortisone injected at 8th day of incubation, cortisone 2.0 ㎎ injected embryo group revealed more suppression in growth than the group injected 0.5㎎ of cortisone.