The Protective Effect of Ginger Aqueous Extracts on CCl_4-induced Hepatic Damage in Mice

다국어 초록 (Multilingual Abstract)

The purpose of present study is to observe the hepato-protective effect of ginger aqueous extracts on carbon tetrachloride(CCl_4)-induced mouse. Ginger groups received ginger aqueous extracts (500 mg/kg) orally for 3 days and given a single dose of CCl_4 (4 mL/kg). Silymarin group was treated with silymarin (50 mg/kg) orally for 3 days and then aministration of CCl_4 (4 mL/kg). Control group was only administered CCl_4 (4 mL/kg). In the ginger groups, the AST, ALT levels were significantly (p < 0.05) decreased compared to the control groups. Histopathological evaluation,hepatic parenchyma and kidney parenchyma of ginger groups were significantly (p < 0.05) decreased compared to control group. The results obtained in this study suggest that ginger aqueous extracts are able to protect the liver CCl4-induced injury.

참고문헌 (Reference)

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