Phytochemical Constituents of Bistorta manshuriensis

다국어 초록 (Multilingual Abstract)

Phytochemical investigation of the MeOH extract of the aerial parts of Bistorta manshuriensis resultedin the isolation of two cerebrosides, two lactams, six phenolic compounds and seven flavonoids. Their chemicalstructures were characterized by spectroscopic methods to be pinelloside (1), soyacerebroside I (2), pterolactam(3), 5-hydroxypyrrolidine-2-one (4), vanillic acid (5), caffeic acid methyl ester (6), protocatechuic acid (7), caffeicacid (8), 3,5-di-O-caffeoyl quinic acid methyl ester (9), chlorogenic acid methyl ester (10), avicularin (11), afzelin(12), quercetin (13), isoorientin (14), quercetin 3-O-β-D-glucoside (15), quercitrin (16), and luteolin (17). Theisolated compounds (1 - 4, 7, 12, 14) were isolated for the first time from this plant source and the compounds 1 -4, 9 and 10 were first reported from the genus Bistorta. Compound 17 exhibited moderate cytotoxicity andcompound 6 exhibited weak cytotoxicity against four human cancer cell lines in vitro using an SRB bioassay.

참고문헌 (Reference)

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