The role of host defense mechanism against infection of superficial mycosis, such as dermatophytosis, has notbeen clearly known due to the obscure nature between body fluid and site of parasite invasion, above all, the distribution of Trichophyton spe...
The role of host defense mechanism against infection of superficial mycosis, such as dermatophytosis, has notbeen clearly known due to the obscure nature between body fluid and site of parasite invasion, above all, the distribution of Trichophyton species exhibit particular geographic character and incidences of clinical infection associated with age and sex as well as other external factors that host-parasite relationships of dermatophytosis are still far difficult matter to elucidate.
For the purpose to study the interrelation between body fluid and dermatophytes, both M. ferrugineum, and T. rubrum, which are main pathogen to Korean population, were inoculated into sera and human plasma, and observed the growth characteristics of these fungi.
It has been found that most strains of M. ferrugineum have been inhibited in its growth in human sera and plasma as well as in goat sera prominantly as compared with luxuriant growth in rabbit sera, moreover, the submerged growth of mycelial, element of M. ferrugineum predominantly exhibited a chlamydospore formation, however, neither the growth of T. rubrum in sera or in plasma among tested strains has been inhibited nor exhibited particular microconidia formation in submerged culture.