도토리(Quercus serrata Thunb)와 상수리(Quercus acutissima Carruther) 추출물의 항산화와 항당뇨 활성 연구 = Antioxidant and Antidiabetic Activities of Extracts from Quercus serrata Thunb and Q. acutissima Carruther

다국어 초록 (Multilingual Abstract)

This study was conducted to analyze the antioxidant and antidiabetic activities of acorns according to the types of Quercus serrata Thunb (QST) and Q. acutissima Carruther (QAC). The total polyphenol contents of the extracts from QST and QAC were 220.59 and 320.96 mg GAE/g, respectively. The content of total polyphenol of QAC was higher than that of QAC (p<0.001). DPPH (2,2 Diphenyl 1 picrylhydrazyl) radical scavenging activity, reducing power and superoxide dismutase (SOD)-like activity were increased in a concentration-dependent manner by both acorn extracts, and QAC showed high activity in all antioxidant experiments (p<0.05). The inhibitory activities of α-glucosidase and α-amylase were also increased in a concentration-dependent manner, and QAC showed higher inhibitory activity than QST (p<0.05). Our study indicates that QST and QAC are functional food materials with high antioxidant and antidiabetic activities. In addition, QAC has a higher physiological activity than QST.

참고문헌 (Reference)

1 강재란, "용매별 초석잠 추출물의 항산화 및 항당뇨 활성" 한국식품저장유통학회 24 (24): 615-622, 2017

2 김승미, "와송(Orostachys japonicus) 용매별 분획 추출물의 항산화, 항균 및 암세포 독성 비교" 한국자원식물학회 30 (30): 133-143, 2017

3 이은호, "옥광(Castanea crenata) 밤송이 추출물의 생리활성 효과" 한국식품영양과학회 46 (46): 572-580, 2017

4 김옥선, "상수리 쿠키의 항산화활성 및 품질특성" 한국식생활문화학회 27 (27): 225-232, 2012

5 지윤정, "배초향 추출물의 항산화 및 항당뇨 효과" 동아시아식생활학회 30 (30): 297-305, 2020

6 주신윤, "밤 쿠키의 항산화활성 및 품질특성" 한국식생활문화학회 28 (28): 70-77, 2013

7 김진윤, "밤 과육, 껍질 및 밤나무 잎 추출물에 대한 항산화 및 항염증 활성 비교" 한국약용작물학회 22 (22): 8-16, 2014

8 재해종, "도토리의 일반 성분과 도토리 추출물의 기능에 관한 연구 고찰" 한국식품영양학회 29 (29): 58-64, 2016

9 주신윤, "도토리 분말을 첨가한 쿠키의 항산화활성 및 품질특성" 한국식품조리과학회 29 (29): 177-184, 2013

10 심태흠, "도토리 가루의 성분분석과 항산화능 평가" 한국식품과학회 36 (36): 800-803, 2004

11 이연리, "노니가루 70% 에탄올 추출물의 항산화 및 α-Amylase Inhibitory 활성" 한국식품영양학회 33 (33): 210-214, 2020

12 Bhandari MR, "α-glucosidase and α-amylase inhibitory activities of Nepalese medicinal herb pakhanbhed (Bergenia Ciliata, Haw.)" 106 (106): 247-252, 2008

13 Ishartati E, "α-Glucosidase and α-amylase inhibitory activities of jambolan (Syzygium Cumini (L.) SKEELS) fruit and seed" Atlantis Press 256-260, 2021

14 Teng H, "α-Glucosidase and α-amylase inhibitors from seed oil: A review of liposoluble substance to treat diabetes" 57 (57): 3438-3448, 2017

15 Lee YM, "We really need to know our one hundred kinds of trees" Hyeonamsa 394-398, 1995

16 Yoon CW, "Trees and shrubs in Yesan Campus, Kongju National University: 700 Kinds of Trees that Recognize Afforestation, Ecology, and use Together" Geobook 184-200, 2016

17 Swain T, "The phenolic constituents of Prunus domestica. I.—The quantitative analysis of phenolic constituents" 10 (10): 63-68, 1959

18 Beauchamp C, "Superoxide dismutase:Improved assays and an assay applicable to acrylamide gels" 44 (44): 276-287, 1971

19 Shin DH, "Study on Antioxidant effects of acorn (Quercus Acutissima Carruthers) components; I. the separation and identification of tannin components from acorn" 10 (10): 93-101, 1993

20 Oyaizu M, "Studies on products of browning reaction antioxidative activities of products of browning reaction prepared from glucosamine" 44 (44): 307-315, 1986

21 Lee JH, "Some physiological activity of phenolic substances in plant foods" 26 (26): 317-323, 1994

22 Baron AD, "Postprandial hyperglycaemia and α-glucosidase inhibitors" 40 : S51-S55, 1998

23 Lopes GKB, "Polyphenol tannic acid inhibits hydroxyl radical formation from fenton reaction by complexing ferrous ions" 1472 (1472): 142-152, 1999

24 Custódio L, "Phenolic composition, antioxidant potential and in Vitro inhibitory activity of leaves and acorns of Quercus Suber on key enzymes relevant for hyperglycemia and Alzheimer's disease" 64 : 45-51, 2015

25 Rakić S, "Oak acorn, polyphenols and antioxidant activity in functional food" 74 (74): 416-423, 2006

26 양수진, "Mate (Ilex paraguarensis) 에탄올 추출물의 추출조건 최적화" 한국식품저장유통학회 18 (18): 319-327, 2011

27 Takahama U, "Interactions of flavonoids with α-amylase and starch slowing down its digestion" 9 (9): 677-687, 2018

28 Wu M, "Inhibitory effects of acorn (Quercus Variabilis Blume) kernel-derived polyphenols on the activities of α-amylase, α-glucosidase, and dipeptidyl peptidase IV" 43 : 101224-, 2021

29 Laybutt DR, "Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to β-cell survival during chronic hyperglycemia" 51 (51): 413-423, 2002

30 김민정, "In Vitro 항산화능 측정법에 대한 특징 분석과 채소․과일 시료에 대한 적용 사례 고찰" 한국식품영양과학회 40 (40): 1053-1062, 2011

31 Sekowski S, "Hydrolysable tannins change physicochemical parameters of lipid nanovesicles and reduce DPPH radical-Experimental studies and quantum chemical analysis" 1864 (1864): 183778-, 2021

32 Delgado T, "Hazelnut (Corylus Avellana L.) Kernels as a source of antioxidants and their potential in relation to other nuts" 32 (32): 621-626, 2010

33 Zhu Y, "Effects of sources of carbon and nitrogen on production of α-Glucosidase inhibitor by a newly isolated strain of Bacillus subtilis B2" 109 (109): 737-742, 2008

34 Hong JH, "Diabetes and vitamin D" 22 (22): 6-11, 2021

35 Peng Y, "Determination of phenolic compounds in Perilla frutescens L. by capillary electrophoresis with electrochemical detection" 53 (53): 8141-8147, 2005

36 Lee HW, "DPP-4 Inhibitors and the relations between rosiglitazone and the risk of myocardial infarction" 51 (51): 371-376, 2008

37 Oliveira VB, "Chemical composition and inhibitory activities on dipeptidyl peptidase IV and pancreatic lipase of two underutilized species from the Brazilian Savannah: Oxalis cordata A. St.-Hil. and Xylopia aromatica (Lam.) Mart" 105 : 989-995, 2018

38 Dehghan H, "Bioassay-guided purification of α-amylase, α-glucosidase inhibitors and DPPH radical scavengers from roots of Rheum turkestanicum" 117 : 303-309, 2018

39 Sin DH, "Antioxidative activity of various solvent extracts of quercisemen to linoleic Acid" 8 (8): 79-83, 1991

40 Kim SM, "Antioxidants of pine needle extracts according to preparation method" 31 (31): 527-534, 1999

41 Lee YL, "Antioxidant properties of three extracts from Pleurotus citrinopileatus" 40 (40): 823-833, 2007

42 Blois MS, "Antioxidant determinations by the use of a stable free radical" 181 (181): 1199-1200, 1958

43 La Anh H, "Antioxidant and α-amylase inhibitory activities and phytocompounds of Clausena Indica fruits" 7 (7): 10-, 2020

44 Jun Ho Lee, "Antioxidant and Antimicrobial Activities of Fermentation and Ethanol Extracts of Pine Needles (Pinus densiflora)" 한국식품과학회 15 (15): 582-588, 2006

45 Lee DJ, "Antioxidant activity by DPPH assay" 49 (49): 187-194, 2004

46 Salimifar M, "A review on natural products for controlling type 2 diabetes with an emphasis on their mechanisms of actions" 9 (9): 402-411, 2013

47 Korea Centers for Disease Control and Prevention, "2018National health and nutrition survey" Korea centers for Disease control and Prevention 1358-, 2019