COVID-19 Vaccination Rates in Patients With Chronic Medical Conditions: A Nationwide Cross-Sectional Study

다국어 초록 (Multilingual Abstract)

As most individuals acquire immunity to severe acute respiratory syndrome coronavirus 2, South Korea declared a return to normalcy a few months ago. However, epidemic waves continue because of endlessly emerging variants and waning immunity. Health authorities are focusing on those at high risk of severe coronavirus disease 2019 to minimize damage to public health and the economy. In this regard, we investigated the vaccination rates in patients with various chronic medical conditions by examining the national health insurance claims data and the national immunization registry. We found that patients with chronic medical conditions, especially those of higher severity, such as malignancy, had vaccination rates approximately 10–20% lower than those of the general population. Public health authorities and healthcare providers should try to vaccinate these patients to avoid preventable morbidity and mortality.

참고문헌 (Reference)

1 Oosting SF, "mRNA-1273 COVID-19 vaccination in patients receiving chemotherapy, immunotherapy, or chemoimmunotherapy for solid tumours : a prospective, multicentre, non-inferiority trial" 22 (22): 1681-1691, 2021

2 AASLD Expert Panel Consensus Statement, "Vaccines to prevent COVID-19 in patients with liver disease"

3 Williams L, "Towards intervention development to increase the uptake of COVID-19 vaccination among those at high risk : outlining evidence-based and theoretically informed future intervention content" 25 (25): 1039-1054, 2020

4 Kamar N, "Three doses of an mRNA Covid-19 vaccine in solid-organ transplant recipients" 385 (385): 661-662, 2021

5 Mair MJ, "Third dose of SARS-CoV-2 vaccination in hemato-oncological patients and health care workers : immune responses and adverse events-a retrospective cohort study" 165 : 184-194, 2022

6 Espi M, "The ROMANOV study found impaired humoral and cellular immune responses to SARS-CoV-2 mRNA vaccine in virus-unexposed patients receiving maintenance hemodialysis" 100 (100): 928-936, 2021

7 Jin Yong Kim ; Pyoeng Gyun Choe ; Yoonju Oh ; Kyung Joong Oh ; Jinsil Kim ; So Jeong Park ; Ji Hye Park ; Hye Kyoung Na ; Myoung-don Oh, "The First Case of 2019 Novel Coronavirus Pneumonia Imported into Korea from Wuhan, China: Implication for Infection Prevention and Control Measures" 대한의학회 35 (35): 1-4, 2020

8 Mondal P, "Sociodemographic predictors of COVID-19 vaccine acceptance : a nationwide US-based survey study" 198 : 252-259, 2021

9 American Heart Association, "Questions about COVID-19 vaccination"

10 Moujaess E, "Perceptions of the COVID-19 vaccine among patients with cancer : a single-institution survey" 17 (17): 4071-4079, 2021

11 Jung Jiwon ; Jungmin Lee ; Seongmin Jo ; Bae Seongman ; Ji Yeun Kim ; Cha Hye Hee ; Lim Young-Ju ; Kwak Sun Hee ; Hong Min Jee ; Kim Eun Ok ; Bae Joon-Yong ; Kang Changmin ; Sung Minki ; Park Man-Seong ; Kim Sung-Han, "Nosocomial Outbreak of COVID-19 in a Hematologic Ward" 대한감염학회 53 (53): 332-341, 2021

12 Mair MJ, "Humoral immune response in hematooncological patients and health care workers who received SARS-CoV-2 vaccinations" 8 (8): 106-113, 2022

13 National Kidney Foundation, "Health guidance for kidney patients"

14 "Expansion of indication for second booster for prevention of COVID-19 resurgence and call for vaccination (July 13)"

15 Ji Wonjun ; Huh Kyungmin ; Kang Minsun ; Hong Jinwook ; Bae Gi Hwan ; 이예린 ; Na Yewon ; Choi Hyoseon ; Gong Seon Yeong ; Choi Yoon-Hyeong ; Ko Kwang-Pil ; Im Jeong-Soo ; 정재훈, "Effect of Underlying Comorbidities on the Infection and Severity of COVID-19 in Korea: a Nationwide Case-Control Study" 대한의학회 35 (35): 1-15, 2020

16 "Current status of COVID-19 outbreak and vaccination in Korea"

17 "Coronavirus disease-19 (COVID-19)"

18 Chun JY, "Cancer patients’ willingness to take COVID-19 Vaccination: a nationwide multicenter survey in Korea" 13 (13): 3883-, 2021

19 "COVID-19 vaccines for people who are moderately or severely immunocompromised"

20 Aw J, "COVID-19 vaccine hesitancy-A scoping review of literature in high-income countries" 9 (9): 900-, 2021

21 Diesel J, "COVID-19 vaccination coverage among adults-United States, December 14, 2020-May 22, 2021" 70 (70): 922-927, 2021

22 "COVID-19 advice for the public: getting vaccinated"

23 Chan WL, "Acceptance of COVID-19 vaccination in cancer patients in Hong Kong: approaches to improve the vaccination rate" 9 (9): 792-, 2021

24 "ASH-ASTCT COVID-19 vaccination for HCT and CAR T cell recipients: frequently asked questions"