급성 및 아급성 뇌내 혈종의 고자장 자기공명영상에 관한 실험적 연구 = An Experimental Study on High-field MR Imaging of Acute and Subacute Intracerebral Hematoma

다국어 초록 (Multilingual Abstract)

To clarify the findings in acute and subacute intracerebral hematoma on 2.0T MRT, to evaluate the diagnostic value of each pulse sequences, and to obtain the valuable informations determining the age of the lesion, the MRI was performed sequentially in experimental model of intracerebral hematoma. Sixteen cats were used as enperimental animal, and the lesions were made by the injection of arterial blood into the brain parenchyme, The MRI was performed by spin echo technique with TR and TE of 500/30 and 3000/30, 80, and by gradient echo technique with 300/12. The relative signal intensities of hematoma and surrounding parenchyme were calculated as compared with contralateral normal white matter and the findings and differences on the time intervals and imaging techniques were analyzed. Most of the intracerebral hematomas were seen as sio or low intensity on T1 and T2 weighted images immediately after bleeding, and as high intensity on T1 weight image form 4 days to 1 week. The igh intensity of surrounding parenchyme on T1 and T2 weighted images were found upto 1 week and diminished after then. The low signal intensity of peripheral portion of the lesion cannot be explained clearly, however, the boundary effect cue to different susceptibility and the free radicals in macrophages during acute phase and the hemosiderin deposition in subacute phase are thought as the possible cause of the low intensity