Remineralization Effects of Silver Fluoride, Silver Diamine Fluoride, and Sodium Fluoride Varnish

다국어 초록 (Multilingual Abstract)

Objective: This study aimed to compare the remineralization effect of a newly introduced silver fluoride (AgF) agent when applied to dried and saliva-contaminated tooth surfaces with that of silver diamine fluoride (SDF) and sodium fluoride varnish.
Methods: Artificial caries were induced on dentin and enamel using bovine incisors. The specimens were divided into four dentin and four enamel groups, and microhardness was measured. The four groups were categorized into control, AF, DF, and NF. In each group, half of the specimens were treated with fluoride agents on dried surfaces, whereas the other half received the agents on saliva-contaminated surfaces. The control group was treated with distilled water. The AF group was treated with Riva Star AquaTM, consisting of AgF (step 1) and potassium iodide (KI, step 2). The DF group was treated withRiva StarTM, containing SDF (step 1) and KI (step 2). The NF group was treated with Fast Release Varnish. After 7 days of pH cycling, the microhardness was measured again to assess the remineralization effects.
Results: The AF and DF groups showed a significant increase in microhardness compared to the NF and control groups. There was no statistically significant difference between the AF and DF groups. For dentin caries, there was no statistically significant difference between the dry subgroup and the saliva-contaminated subgroup in the AF and DF groups.
Conclusion: The novel AgF agent can be effectively used for remineralization of dentin and enamel carious lesions, despite the presence of saliva contamination in dentin caries.