Gold Nanoshell-Mediated Photothermal Therapy for Facial Pores

다국어 초록 (Multilingual Abstract)

Facial pores are a visible topographic feature of skin surfaces and are generally the enlarged openings of pilosebaceous follicles. Enlarged facial pores can be a significant cosmetic problem, particularly for women. Recently, gold nanoshell-mediated photothermal therapy (PTT) has been reported to be effective in treating recurrent acne. The treatment of enlarged facial pores with gold nanoshell-mediated PTT produced excellent results with no side effects. The two cases reported here demonstrate the possibility of gold nanoshell-mediated PTT as a safe and effective treatment for enlarged facial pores.

참고문헌 (Reference)

1 Fuchs CSK, "Transfollicular delivery of gold microparticles in healthy skin and acne vulgaris, assessed by in vivo reflectance confocal microscopy and optical coherence tomography" 2019

2 Huang X, "Plasmonic photo-thermal therapy (PPTT) using gold nanoparticles" 23 : 217-228, 2008

3 Sharifi M, "Plasmonic gold nanoparticles: optical manipulation, imaging, drug delivery and therapy" 311-312 : 170-189, 2019

4 Lee SJ, "Facial pores:definition, causes, and treatment options" 42 : 277-285, 2016

5 Sugata K, "Confocal laser microscopic imaging of conspicuous facial pores in vivo: relation between the appearance and the internal structure of skin" 14 : 208-212, 2008

6 Sugiyama-Nakagiri Y, "Age-related changes in the epidermal architecture around facial pores" 50 : 151-154, 2008

7 Fuchs CSK, "Acne treatment with light absorbing gold microparticles and optical pulses: an open-label European multi-centered study in moderate to moderately severe acne vulgaris patients" 51 : 686-693, 2019

8 Paithankar DY, "Acne treatment based on selective photothermolysis of sebaceous follicles with topically delivered light-absorbing gold microparticles" 135 : 1727-1734, 2015