한국형 DASH 교육 프로그램이 여성노인의 산화스트레스, 항산화능력과 호모시스테인 농도에 미치는 효과 = The Effects of Korean DASH Diet Education Program on Oxidative Stress, Antioxidant Capacity, and Serum Homocysteine Level among Elderly Korean Women

다국어 초록 (Multilingual Abstract)

Purpose: The purpose of this study was to investigate the effects of the Korean Dietary Approaches to Stop Hypertension (DASH) education program on oxidative stress, antioxidant capacity, and serum homocysteine (Hcy) level in elderly Korean women. Methods: This was a quasi-experimental study employing non-equivalent control group pretest-posttest design. The DASH group (n= 27) underwent the DASH education program for 12 weeks, whereas the control group (n= 21) was provided one education session. The survey was conducted before and after the intervention period. Results: In DASH group, monounsaturated fatty acid (MUFA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) intakes significantly increased after the intervention as compared to prior to the intervention. No significant differences were found in the control group. After the intervention, thiobarbituric acid reactive substance (TBARS) and Hcy levels significantly decreased in the DASH group but not in the control group. Conclusion: The DASH education program was effective in reducing oxidative stress and Hcy levels in elderly Korean women.

참고문헌 (Reference)

1 김다혜, "일부 노인의 저작강도별 음식섭취능력과 잔존치아수가 구강건강관련 삶의 질에 미치는 영향" 한국치위생과학회 16 (16): 53-61, 2016

2 윤군애, "성인 남성의 교육수준 및 생활습관에 따른 비만위험도" 한국영양학회 37 (37): 385-393, 2004

3 최승혜, "만성 뇌졸중 환자의 항산화능에 영향을 주는 요인에 관한 연구" 기초간호학회 16 (16): 52-59, 2014

4 최정숙, "고령인구 비율이 높은 지역 성인 및 노인의 계절별 영양소 섭취실태" 한국식품영양과학회 33 (33): 668-678, 2004

5 Krzysztof Mazurek, "Zmniejszenie ryzyka sercowo-naczyniowego wśród nieaktywnych fizycznie kobiet w okresie pomenopauzalnym podczas zorganizowanej aktywności fizycznej" VM Media SP. zo.o VM Group SK 75 (75): 476-485, 2017

6 최스미, "The effects of the DASH diet education program with omega-3 fatty acid supplementation on metabolic syndrome parameters in elderly women with abdominal obesity" 한국영양학회 9 (9): 150-157, 2015

7 Jennifer L Troyer, "The effect of home-delivered Dietary Approach to Stop Hypertension (DASH) meals on the diets of older adults with cardiovascular disease" Oxford University Press (OUP) 91 (91): 1204-1212, 2010

8 Iris F.F. Benzie, "The Ferric Reducing Ability of Plasma (FRAP) as a Measure of “Antioxidant Power”: The FRAP Assay" Elsevier BV 239 (239): 70-76, 1996

9 Miller DM, "Studies of ascorbate-dependent, iron-catalyzed lipid peroxidation" 271 (271): 113-119, 1989

10 Moselhy SS, "Plasma homocysteine and oxidative stress in cardiovascular disease" 19 (19): 27-31, 2003

11 Cabello-Verrugio C, "Oxidative stress in disease and aging: mechanisms and therapies" 2016 : 1-2, 2016

12 Ji LL, "Oxidative stress and aging. Role of exercise and its influences on antioxidant systems" 854 (854): 102-107, 1998

13 H. A. Al-Aubaidy, "Oxidative DNA damage and obesity in type 2 diabetes mellitus" Bioscientifica 164 (164): 899-904, 2011

14 Mesia M. Steed, "Mechanisms of Cardiovascular Remodeling in Hyperhomocysteinemia" Mary Ann Liebert Inc 15 (15): 1927-1943, 2011

15 J.-C. Guilland, "L’hyperhomocystéinémie : facteur de risque cardiovasculaire ou simple marqueur ?" Elsevier BV 51 (51): 111-121, 2003

16 Ministry of Health and Welfare, Korea Centers for Disease Control and Prevention, "Korea Health Statistics 2015: Korea National Health and Nutrition Examination Survey (KNHANES VI-3)" Korea Centers for Disease Control and Prevention 2016

17 CORA L. CRAIG, "International Physical Activity Questionnaire: 12-Country Reliability and Validity" Ovid Technologies (Wolters Kluwer Health) 35 (35): 1381-1395, 2003

18 O. Stanger, "Effects of Folate Treatment and Homocysteine Lowering on Resistance Vessel Reactivity in Atherosclerotic Subjects" American Society for Pharmacology & Experimental Therapeutics (ASPET) 303 (303): 158-162, 2002

19 Mahmoud A. Alomari, "Effect of physical activity on levels of homocysteine, folate, and vitamin B 12 in the elderly" Informa UK Limited 44 (44): 68-73, 2016

20 Bonanome A, "Effect of dietary monounsaturated and polyunsaturated fatty acids on the susceptibility of plasma low density lipoproteins to oxidative modification" 12 (12): 529-533, 1992

21 F. J. García-Alonso, "Effect of consumption of tomato juice enriched with n-3 polyunsaturated fatty acids on the lipid profile, antioxidant biomarker status, and cardiovascular disease risk in healthy women" Springer Nature 51 (51): 415-424, 2012

22 David J.A. Jenkins, "Effect of Current Dietary Recommendations on Weight Loss and Cardiovascular Risk Factors" Elsevier BV 69 (69): 1103-1112, 2017

23 Tao Huang, "Docosahexaenoic acid decreases plasma homocysteine via regulating enzyme activity and mRNA expression involved in methionine metabolism" Elsevier BV 26 (26): 112-119, 2010

24 Ephraim Yavin, "Docosahexaenoic Acid Abundance in the Brain: A biodevice to Combat Oxidative Stress" Informa UK Limited 5 (5): 149-157, 2013

25 Frank M. Sacks, "Dietary Fats and Cardiovascular Disease: A Presidential Advisory From the American Heart Association" Ovid Technologies (Wolters Kluwer Health) 136 (136): e1-e23, 2017

26 Ji Zhou, "Contributions of hyperhomocysteinemia to atherosclerosis: Causal relationship and potential mechanisms" Wiley-Blackwell 35 (35): 120-129, 2009

27 The Korean Nutrition Society, "Computer aided nutritional analysis program (CAN-Pro) version 3.0. [software]" The Korean Nutrition Society 2007

28 Clarkson PM, "Antioxidants and physical performance" 35 (35): 131-141, 1995

29 Kevin C. Kregel, "An integrated view of oxidative stress in aging: basic mechanisms, functional effects, and pathological considerations" American Physiological Society 292 (292): R18-R36, 2007

30 Elizabeth A. Baker, "Adaptation of a Modified DASH Diet to a Rural African American Community Setting" Elsevier BV 51 (51): 967-974, 2016