5-Benzofuryl-2-[1-(alkoxyimino)alkyl]-3-hydroxycyclohex-2-en-1-one 유도체 중 2,3-dihydro-2,2,4,6,7-pentamethylbenzofuran-5-yl 치환체들의 제초활성에 관한 구조-활성관계

다국어 초록 (Multilingual Abstract)

A some of synthesized 2,3-dihydro-2,2,4,6,7-pentamethylbenzofuran-5-yl substituents in 5-benzofuryl-2-[1-(alkoxyimino)alkyl]-3-hydroxycyclohex-2-en-1-one derivatives as substrates were found to show herbicidal activity against rice plant (Oryza sativa L.) and barnyard grass (Echinochloa crus-galli) with post emergence under submerged conditions. The substrate with R₁=methyl substituents, 1~5 showed the higher herbicidal activity to the seed, 3 leaf stage of rice plant and barnyard grass. The structure activity relationships (SARs) on the herbicidal activity of R₁ and R₂ on the azomethine bond in substrate were analysized. In the condition of R₁ groups are same, the herbicidal activity against 3 leaf stage of rice plant were governed by the optimal hydrophobicity ((logP)<SUB>opt.</SUB>=4.57). Whereas, in the case of barnyard grass, the herbicidal activities were largely dependent upon the steric effect, B₂ constant than hydrophobicity. In order to take the selective herbicidal activity between rice plant and barnyard grass, it is assumed that the (S) should be a round shape with higher hydrophobicity (logP＞4.57) than optimal value. Also, the R₁ groups must be small and the R₂ groups are advisable to be unsaturate.