Advances in the simulation of light–tissue interactions in biomedical engineering

다국어 초록 (Multilingual Abstract)

Monte Carlo (MC) simulation for light propagation in scattering and absorbing media is the gold standard for studying theinteraction of light with biological tissue and has been used for years in a wide variety of cases. The interaction of photonswith the medium is simulated based on its optical properties and the original approximation of the scattering phase function.
Over the past decade, with the new measurement geometries and recording techniques invented also the correspondingsophisticated methods for the description of the underlying light–tissue interaction taking into account realistic parametersand settings were developed. Applications, such as multiple scattering, optogenetics, optical coherence tomography, Ramanspectroscopy, polarimetry and Mueller matrix measurement have emerged and are still constantly improved. Here, we reviewthe advances and recent applications of MC simulation for the active fi eld of the life sciences and the medicine pointing outthe new insights enabled by the theoretical concepts.

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