The authors describe a synergistic system for nanoparticle based chiral separation. It is based on the use of a conventional chiral selector hydroxyproyl‐β‐cyclodextrin and a kind of gold nanoparticle functionalized with D‐penicillamine as an a...
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https://www.riss.kr/link?id=O112849743
2020년
-
0173-0835
1522-2683
SCI;SCIE;SCOPUS
학술저널
1060-1066 [※수록면이 p5 이하이면, Review, Columns, Editor's Note, Abstract 등일 경우가 있습니다.]
0
상세조회0
다운로드다국어 초록 (Multilingual Abstract)
The authors describe a synergistic system for nanoparticle based chiral separation. It is based on the use of a conventional chiral selector hydroxyproyl‐β‐cyclodextrin and a kind of gold nanoparticle functionalized with D‐penicillamine as an a...
The authors describe a synergistic system for nanoparticle based chiral separation. It is based on the use of a conventional chiral selector hydroxyproyl‐β‐cyclodextrin and a kind of gold nanoparticle functionalized with D‐penicillamine as an additive. This nanomaterial displays a synergistic effect on the efficiency of the enantioseparation of the chiral drugs amlodipine, tropicamide, and ofloxacin. A comparative study on the enantioseparation capability of three separation systems, viz. (a) single hydroxyproyl‐β‐cyclodextrin system, (b) achiral citrate capped gold nanoparticle/ hydroxyproyl‐β‐cyclodextrin system, and (c) chiral D‐penicillamine functionalized gold nanoparticle/ hydroxyproyl‐β‐cyclodextrin system was performed. The results show that the D‐penicillamine functionalized gold nanoparticle/hydroxyproyl‐β‐cyclodextrin synergistic system has remarkable superiority. The effects of concentrations of D‐penicillamine functionalized gold nanoparticle and hydroxyproyl‐β‐cyclodextrin, of buffer pH value and concentration, and of applied voltage on the performance of enantioseparation were investigated.
Contents: Electrophoresis 12'20
Editorial Board: Electrophoresis 12'20