KSNM60 in Non-thyroidal Radionuclide Therapy: Leaping into the Future

다국어 초록 (Multilingual Abstract)

This year, the Korean Society of Nuclear Medicine (KSNM) is celebrating its 60th anniversary. Treatment, as well as diagnosis, has played a very important role in the development of nuclear medicine. Since I-131 was used for thyroid therapy in 1959, other radionuclide therapy is still being used, and attempts to use new radionuclide are increasing. In this review, we briefly summarize and introduce the therapies such as radioimmunotherapy, transarterial radioembolization, radionuclide therapy for neuroendocrine tumors, peptide receptor radionuclide therapy, control of metastatic bone pain, radiation synovectomy, radionuclide brachytherapy, alpha particle therapy, and boron neutron capture therapy, which has been being attempted so far in the field of nuclear medicine.

참고문헌 (Reference)

1 김근호, "재발한 악성 갈색세포종 환자에서 131I-Metaiodobenzylguanidine (131I-MIBG) 치료 후 131I-MIBG와 18F-FDG PET/CT 영상의 차이점" 대한핵의학회 43 (43): 582-587, 2009

2 Sung Hoon Kim, "Usefulness of F-18 FDG PET/CT in the Evaluation of Early Treatment Response After Interventional Therapy for Hepatocellular Carcinoma" 대한핵의학회 46 (46): 102-110, 2012

3 Young Chul Kim, "Usefulness of Bremsstrahlung Images after Intra-arterial Y-90 Resin Microphere Radioembolization for Hepatic Tumors" 대한핵의학회 45 (45): 59-67, 2011

4 Jung JY, "Therapy region monitoring based on PET using 478 keV single prompt gamma ray during BNCT : A Monte Carlo simulation study" 32 : 562-567, 2016

5 Chul-Hee Lee, "The Feasibility of 64 Cu-PSMA I&T PET for Prostate Cancer" Mary Ann Liebert Inc 2021

6 Yoo J, "Synthesis of stable platinum complexes containing carborane in a carrier group for potential BNCT agents" (25) : 4978-4986, 2009

7 이승홍, "Semi-Quantitative Analysis of Post-Transarterial Radioembolization 90Y Microsphere Positron Emission Tomography Combined with Computed Tomography (PET/CT) Images in Advanced Liver Malignancy: Comparison With 99mTc Macroaggregated Albumin (MAA) Single Photon Emission Computed Tomography (SPECT)" 대한핵의학회 50 (50): 63-69, 2016

8 Won JH, "Self-expandable covered metallic esophageal stent impregnated with beta-emitting radionuclide : an experimental study in canine esophagus" 53 : 1005-1013, 2002

9 Kang HJ, "Repeated radioimmunotherapy with 131I-rituximab for patients with low-grade and aggressive relapsed or refractory B cell non-Hodgkin lymphoma" 71 : 945-953, 2013

10 Lee JD, "Radionuclide therapy of skin cancers and Bowen’s disease using a specially designed skin patch" 38 : 697-702, 1997

11 Kang HJ, "Radioimmunotherapy with 131I-rituximab for patients with relapsed/refractory B-cell non-Hodgkin’s lymphoma(NHL)" 7 : 136-145, 2011

12 Shin DY, "Radioimmunotherapy with 131I-rituximab as consolidation therapy for patients with diffuse large B-cell lymphoma" 78 : 825-831, 2016

13 Kim DY, "Radioembolization with yttrium-90 resin microspheres in hepatocellular carcinoma : a multicenter prospective study" 38 : 495-501, 2015

14 Cho YY, "Radioembolization is a safe and effective treatment for hepatocellular carcinoma with portal vein thrombosis : a propensity score analysis" 11 : e0154986-, 2016

15 Lee E, "Radiation safety analysis for the A-BNCT facility in Korea" 142 : 92-103, 2018

16 Kim G, "Production of alpha-particle emitting 211At using 45 MeV alpha-beam" 59 : 2849-2860, 2014

17 Jeong JM, "Preparation of rhenium-188-tin colloid as a radiation synovectomy agent and comparison with rhenium-188-sulfur colloid" 52 : 851-855, 2000

18 Sohn JH, "Phase II study of transarterial holmium-166-chitosan complex treatment in patients with a single, large hepatocellular carcinoma" 76 : 1-9, 2009

19 Lee T, "Performance evaluation of a Compton SPECT imager for determining the position and distribution of 225Ac in targeted alpha therapy : a Monte Carlo simulation based phantom study" 154 : 108893-, 2019

20 Lee W, "PEGylated liposome encapsulating nido-carborane showed significant tumor suppression in boron neutron capture therapy(BNCT)" 522 : 669-675, 2020

21 Kim KO, "Optimized therapeutic neutron beam for accelerator-based BNCT by analyzing the neutron angular distribution from 7Li(p, n)7Be reaction" 67 : 1173-1179, 2009

22 Kim JK, "Long-term clinical outcome of phase iib clinical trial of percutaneous injection with holmium-166/chitosan complex(Milican)for the treatment of small hepatocellular carcinoma" 12 : 543-548, 2006

23 Lee JW, "Incorporation of high-dose 131I-metaiodobenzylguanidine treatment into tandem high-dose chemotherapy and autologous stem cell transplantation for high-risk neuroblastoma : results of the SMC NB-2009 study" 10 : 108-, 2017

24 Ji Won Lee, "Incorporation of high-dose 131I-metaiodobenzylguanidine treatment into killer immunoglobulin-like receptor/HLA-ligand mismatched haploidentical stem cell transplantation for children with neuroblastoma who failed tandem autologous stem cell transplantatio" Wiley 64 (64): e26399-, 2017

25 Minseok Suh, "Head to head comparison of 68Ga-NGUL and 68Ga-PSMA-11 in patients with metastatic prostate cancer: a prospective study" Society of Nuclear Medicine 62 (62): 1457-1460, 2021

26 Yoon DK, "GPU-based prompt gamma ray imaging from boron neutron capture therapy" 42 : 165-169, 2015

27 Suh JK, "Feasibility and effectiveness of treatment strategy of tandem highdose chemotherapy and autologous stem cell transplantation in combination with 131I-MIBG therapy for high-risk neuroblastoma" 24 : e13658-, 2020

28 Lee JT, "Experimental and clinical studies on the intraarterial injection of holmium-166 chitosan complex in the treatment of hepatocellular carcinoma" 44 : 441-451, 2001

29 Shin JH, "Effects of irradiation using a radioisotope-filled balloon on tissue hyperplasia caused by stent placement in a canine urethral model" 47 : 436-443, 2006

30 Kim W, "Effects of beta-radiation using a holmium-166 coated balloon on neointimal hyperplasia in a porcine coronary stent restenosis model" 67 : 625-629, 2003

31 Won JH, "Effects of a holmium-166 incorporated covered stent placement in normal canine common bile ducts" 16 : 705-711, 2005

32 Chang YS, "Effect of carrier on labeling and biodistribution of Re-188-hydroxyethylidene diphosphonate" 34 : 344-352, 2000

33 Kim MH, "Dual-labeled prostate-specific membrane antigen(PSMA)-targeting agent for preoperative molecular imaging and fluorescence-guided surgery for prostate cancer" 64 : 4-13, 2021

34 Lee I, "Comparisons of 131I-rituximab treatment responses in patients with aggressive lymphoma and indolent lymphoma" 33 : 881-890, 2019

35 Shehta A, "Bridging and downstaging role of trans-arterial radio-embolization for expected small remnant volume before liver resection for hepatocellular carcinoma Ann Hepatobiliary" 24 : 421-430, 2020

36 Lee DJ, "An accelerator-based epithermal neutron beam design for BNCT and dosimetric evaluation using a voxel head phantom" 110 : 655-660, 2004

37 Lee H, "A pancancer analysis of the clinical and genetic portraits of somatostatin receptor expressing tumor as a potential target of peptide receptor imaging and therapy" 10 : 42-, 2020

38 Kim W, "A novel method of brachytherapy using local delivery of 99mTc-HMPAO for coronary stent restenosis" 19 : 179-188, 2004

39 Kim EH, "A microdosimetric approach to the thermal neutron fluence prescription for clinical BNCT" 112 : 377-383, 2004

40 Lee I, "A microdose clinical trial to evaluate [18F] Florastamin as a positron emission tomography imaging agent in patients with prostate cancer" 48 : 95-102, 2021

41 Lee BS, "18F-labeled 1, 2, 3-triazole-linked Glu-urea-Lys-based PSMA ligands have good pharmacokinetic properties for positron emission tomography imaging of prostate cancer" 80 : 1383-1393, 2020

42 Sudhakara Reddy Seelam, "188Re Labeled liver therapeutic drugs for hepatic carcinoma (HCC)" 대한방사성의약품학회 5 (5): 26-35, 2019

43 Yoon JK, "131I-MIBG therapy in malignant pheochromocytoma and medullary thyroid carcinoma" 29 : 319-327, 1995

44 Chung HW, "131I-MIBG targeting of neuroblastoma cells is acutely enhanced by KCl stimulation through the calcium/calmodulin-dependent kinase pathway" 28 : 488-493, 2013