좌심실내 혈류 전파 속도에 관한 연구 = A Study on the Left Ventricular Flow Propagation Velocity

다국어 초록 (Multilingual Abstract)

Background : Noninvasive attemps to identify left ventricular relaxation have been hampered because relaxation rate, left atrial filling pressure, and chamber compliance are the major determinants of peak early velocity and filling rate. This study was perfomed to evaluate the relation between the velocity of flow propagation and left ventricular relaxation by using pulsed doppler echocardiography to analize flow propagation in the left ventricle.
Method : By using pulsed Doppler echocardiography, the velocity of left ventricular flow propagation was measured from the distance and time difference of flow wave along the long axis propagation of left ventricular inflow during early filling in normal subjects (n=30), and M-mode echocardiographic data were obtained to evaluate mitral annulus long axis movement (mitral annulus relaxation rate) which represents left ventricular relaxation.
Results : the peak early velocity was not related to mitral annulus relaxation rate, but, the velocity of flow propagation was related to mitral annulus relaxarate (P<0.005) in normal subjects.
Conclusion : the velocity of flow propagation during early filling seems to be highly dependent on the mitral annulus relaxation rate and could be an important noninvasive tool in studying diastolic function.