Skeletal Development - Wnts Are in Control

참고문헌 (Reference)

1 "Wnt9a signaling is required for joint integ-rity and regulation of Ih during chondrogenesis" 133 : 30393049-, 2006b

2 "Wnt/beta-catenin signaling is sufficient and necessary for synovial joint formation" 18 : 24042417-, 2004

3 "Wnt/beta-catenin signaling interacts differentialy with Ihh signaling in controlling endochondral bone and synovial joint formation" 133 : 36953707-, 2006

4 "Wnt/ beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte diferentiation during vertebrate skeletogenesis" 8 : 739750-,

5 "Wnt-7a causes loss of diferentiated phenotype and inhibits apoptosis of articular chondrocytes via different mechanisms" 279 : 2659726604-, 2004

6 "Wnt-5a is involved in TGF-beta3-stimulated chon-drogenic differentiation of chick wing bud mesenchymal cells" 38 : 183195-, 2006

7 "Wnt-3a regulates chondrocyte diferentiation via c-Jun/AP-1 pathway" 579 : 48374842-, 2005a

8 "Wnt-14 plays a pivotal role in inducing synovial joint formation in the developing appendicular skeleton" 104 : 341351-, 2001

9 "Wnt signalling path-way: a new target for the treatment of osteoporosis" 9 : 10631077-,

10 "Wnt signaling in osteoblasts and bone diseases" 341 : 184 -,

11 "Wnt signaling and os-teoblastogenesis" 7 : 3339-, 2006

12 "Wnt sig-naling: a key regulator of bone mass" 76 : 103127-, 2006

13 "Wnt regulation of limb mesenchymal chondrogenesis is acompanied by altered N-cadherin-related functions" 15 : 14361438-, 2001

14 "Wnt regulation of chondrocyte differentiation" 115 : 48094818-, 2002

15 "Transcriptional mechanisms of chondrocyte differentiation" 19 : 389394-, 2000

16 "The genetics of low-density lipoprotein receptor-related protein 5 in bone: a story of extremes" 148 : 26222629-, 2007

17 "The Wnt signaling pathway in development and disease" 20 : 781810-, 2004

18 "The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice" 18 : 12221237-, 2004

19 "The Wnt antagonist Frzb-1 regulates chondrocyte maturation and long bone development during limb skeletogenesis" 251 : 142156-, 2002

20 "Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton" 148 : 2635243-,

21 "TOPGAL mice show that the canonical Wnt signaling pathway is active during bone development and growth and is activated by mechanical loading in vitro" 20 : 1103113-, 2005

22 "Sox9 is required for cartilage formation" 22 : 8589-, 1999

23 "Sequential roles of Hedgehog and Wnt signaling in os-teoblast development" 132 : 4960-, 2005

24 "Secreted frizzled related protein 1 regulates Wnt sig-naling for BMP2 induced chondrocyte differentiation" 208 : 8796-,

25 "Scle-rostin binds to LRP5/6 and antagonizes canonical Wnt sig-naling" 280 : 1988319887-, 2005b

26 "SOST/sclerostin, an osteocyte-derived negative regulator of bone formation" 16 : 319327-, 2005

27 "Role of canonical Wnt-signalling in joint formation" 12 : 7180-, 2006a

28 "Requirement for beta-catenin in anterior-posterior axis formation in mice" 148 : 567578-, 2000

29 "Regulation of the chondrocyte phenotype by beta-catenin" 129 : 55415550-, 2002

30 "Regulation of bone mas by Wnt signaling" 116 : 12021209-, 2006

31 "Regulation of beta-catenin signaling and maintenance of chondrocyte differentiation by ubiquitin-independent pro-teasomal degradation of alpha-catenin" 280 : 1275812765-, 2005b

32 "Reaching a genetic and molecular understanding of skeletal development" 2 : 389406-, 2002

33 "PTHrP and skeletal development" 1068 : 113-, 2006

34 "Opposing roles of WNT-5A and WNT-1 in interleukin-1beta regulation of type II cola-gen expression in articular chondrocytes" 281 : 2203922047-, 2006

35 "Noncanonical Wnt signaling through G pro-tein-linked PKCdelta activation promotes bone formation" 12 : 113127-, 2007

36 "Non-canonical WNT-4 signaling enhances bone re-generation of mesenchymal stem cells in craniofacial defects through activation of p38 MAPK" 282 : 30938-30948, 2007

37 "Molecular bases of the regulation of bone remodeling by the canonical Wnt sig-naling pathway" 73 : 4384-, 2006

38 "Lrp5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in mice" 102 : 17406-17411, 2005

39 "Long-term in vitro analysis of limb cartilage development: involvement of Wnt signaling" 93 : 526541-, 2004

40 "Lack of beta-catenin affects mouse devel-opment at gastrulation" 121 : 35293537-, 1995

41 "LRP5 and Wnt signaling: a union made for bone" 19 : 17491757-, 2004

42 "LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development" 107 : 513523-,

43 "Involvement of Wnt-5a in chondrogenic pat-tern formation in the chick limb bud" 41 : 2940-, 1999

44 "Interactions betwen Sox9 and beta-catenin control chondrocyte diferentiation" 18 : 1072-1087, 2004

45 "Inhibition of chondro-genesis by Wnt gene expression in vivo and in vitro" 185 : 104118-, 1997

46 "Indian hedgehog: its roles and regulation in endochondral bone development" 96 : 11631173-, 2005

47 "Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone for-mation" 13 : 20722086-, 1999

48 "Homozygosity for the Min allele of Apc results in disruption of mouse development prior to gastrulation" 203 : 422433-, 1995

49 "Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization" 98 : 66986703-, 2001

50 "Genetic control of skele-tal development" 11 : 527532-, 2001

51 "Endocrine regulation of energy metabolism by the skeleton" 130 : 456469-, 2007

52 "Dual roles of Wnt signal-ing during chondrogenesis in the chicken limb" 127 : 31413159-, 2000

53 "Downregulation of Wnt signaling by increased expression of Dickkopf-1 and -2 is a prerequisite for late-stage osteoblast diferentiation of KS483 cells. J. Bone Miner. Res. 20" 186777 J. Bone Miner. Res. : 20-, 2005

54 "Dkk2 has a role in terminal osteoblast diferentiation and mineral-ized matrix formation" 37 : 945952-, 2005a

55 "Distinct roles for Hedgehog and canonical Wnt signaling in specification, dif-ferentiation and maintenance of osteoblast progenitors" 133 : 32313244-,

56 "Developmental regulation of the growth plate" 423 : 332336-, 2003

57 "Developmental regulation of Wnt/beta-catenin signals is required for growth plate assembly, cartilage integ-rity, and endochondral ossification" 280 : 19185-19195, 2005

58 "Development of synovial joints" 69 : 144155-,

59 "Deletion of a single alele of the Dkk1 gene leads to an increase in bone formation and bone mass" 21 : 934945-, 2006

60 "Canonical Wnt/beta-catenin signaling pre-vents osteoblasts from diferentiating into chondrocytes" 8 : 727738-, 2005

61 "Canonical Wnt signaling in diferentiated os-teoblasts controls osteoclast differentiation" 8 : 751-764, 2005

62 "Canonical WNT signaling promotes os-teogenesis by directly stimulating RUNX2 gene expression" 280 : 3313233140-, 2005

63 "Bone regeneration is regulated by Wnt signaling" 2007

64 "Bone mass is inversely propor-tional to Dkk1 levels in mice" 41 : 331339-, 2007

65 "Beta-catenin signaling plays a disparate role in dif-ferent phases of fracture repair: implications for therapy to improve bone healing" 4 : e249-,

66 "BMP receptor signaling is required for postnatal maintenance of articular cartilage" 2 : e355-, 2004

67 "AP-1 transcription factor complex is a target of sig-nals from both WnT-7a and N-cadherin-dependent cell-cell adhesion complex during the regulation of limb mesenchy-mal chondrogenesis" 273 : 197203-, 2002

68 "A Wnt canon orchestrating osteoblasto-genesis" 16 : 151-158, 2006