Safety Assessment of Mainstream Smoke of Herbal Cigarette

다국어 초록 (Multilingual Abstract)

Owing to the increase in price of cigarettes in Korea, herbal cigarettes have received increasing attentionas a non-smoking aid; however, its safety has hardly been studied. We analyzed some of the toxic componentsin the mainstream smoke of herbal cigarettes, performed a mutagenicity test on smoke condensatesfor safety assessment, and compared the results with the corresponding values of a general cigarette withthe same tar content. Herbal cigarette “A” was smoked using automatic smoking machine under ISO conditionsin a manner similar to general cigarette “T”. The tar content measured was higher than thatinscribed on the outside of a package. The mainstream smoke of herbal cigarette “A” did not containdetectable levels of tobacco-specific nitrosamines and nicotine. Carbon monoxide and benzo(α)pyrenecontents in herbal cigarette “A” were higher than those in the general cigarette “T”. The phenolic contentssuch as hydroquinone, resorcinol, and catechol in herbal cigarette “A” were higher than those in the generalcigarette “T”, but cresol contents in herbal cigarette “A” were lower than those in the general cigarette“T”. The content of aromatic amines such as 4-aminobiphenyl in herbal cigarette “A” was higher thanthat in the general cigarette “T”; however, this difference was not statistically significant. On the otherhand, 1-aminonaphthalene, 2-aminonaphthalene, and 3-aminobiphenyl contents in herbal cigarette “A”were lower than those in the general cigarette “T”. The smoke condensates of herbal cigarette “A” exhibiteda higher mutagenic potential than the condensates from the general cigarette “T” at the same concentration. We concluded that the mainstream smoke of herbal cigarette contains some toxic components, thesmoke condensates of herbal cigarettes are mutagenic similar to general cigarette because of combustionproducts, and that the evaluation of the chemical and biological safety of all types of herbal cigarettesavailable on the market.

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