쌀 알레르기가 동반된 아토피피부염 1례 = A Case of Atopic Dermatitis with Rice Allergy

국문 초록 (Abstract)

저자들은 아토피피부염 환아에서 이유식의 시작과 함께 증상의 악화를 보여 쌀을 포함하는 다중 식품알레르기로 진단된 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

다국어 초록 (Multilingual Abstract)

Rice is a popular food all over the world. Rice is regarded as hypoallergenic and rice hypersensitivity is not common. We experienced a case of multiple food allergy including cow's milk, egg white, buckwheat, soybean and rice. The 8 month-old boy presenting with atopic dermatitis developed recurrent wheezing later. Laboratory findings showed a high serum level of total IgE (561 kU/L), and high levels of specific IgE to rice (11.0 kU/L), egg white (13.0 kU/L), cow's milk (5.73 kU/L), buckwheat (5.45 kU/L), and soybean (25.5 kU/L) using the immune-CAP system. Foods causing allergic reaction were absolutely eliminated and substituted with hypoallergic formula milk. Thereafter, his skin lesions began to improve, and 5 months later, he was tolerable to eat rice. However, he developed recurrent wheezing at the age of 23 months. At now 4 years, he is regularly followed up without any symptoms of food allegy.

참고문헌 (Reference)

1 염혜영, "쌀과 저항원성 쌀 및 유전자 재조합 쌀의알레르기 항원성의 비교" 대한 소아알레르기 호흡기학회 15 (15): 117-125, 2005

2 Ikezawa Z, "Usefulness of hypoallergenic rice (AFT-R 1) and analysis of the salt insoluble rice allergen molecule" 48 : 40-49, 1999

3 Sampson HA, "Update on food allergy" 113 : 805-819, 2004

4 Kim SH, "The sensitization rates of food allergens in a Korean population:a multi-center study" 23 : 502-514, 2003

5 Hill DJ, "The frequency of food allergy in Australia and Asia" 4 : 101-110, 1997

6 Varjonen E, "Skin-prick test and RAST responses to cereals in children with atopic dermatitis. Characterization of IgE-binding components in wheat and oats by an immunoblotting method" 25 : 1100-1107, 1995

7 Andre F, "Role of new allergens and of allergens consumption in the increased incidence of food sensitizations in France" 93 : 77-83, 1994

8 Matsumura T, "Rice pollen asthma" 7 : 7-16, 1969

9 Di Lernia V, "Immunologic contact urticaria syndrome from raw rice" 27 : 196-, 1992

10 Kilshaw PJ, "Effect of heat treatment of cow's milk and whey on the nutrional quality and antigenic properties" 57 : 842-847, 1982

11 Lehrer SB, "Corn allergens: IgE antibody reactivity and cross-reactivity with rice, soy, and peanut" 118 : 298-299, 1999

12 Ikezawa Z, "Clinical effect of hypoallergenic rice (HRS-1) in atopic dermatitis. HRS-1 Research Group" 40 : 633-642, 1991

13 Arai T, "Bronchial asthma induced by rice" 37 : 98-101, 1998

14 Wuthrich B, "Ballmer-Weber B. Isolated allergy to rice" 57 : 263-264, 2002

15 Lezaun A, "Asthma and contact urticaria caused by rice in a housewife" 49 : 92-95, 1994

16 Lezaun A, "Asthma and contact urticaria caused by rice in a housewife" 49 : 92-95, 1994

17 Fiocchi A, "Anaphylaxis to rice by inhalation" 111 : 193-195, 2003

18 Fiocchi A, "Anaphylaxis to rice by inhalation" 111 : 193-195, 2003

19 Ikezawa Z, "A probable involvement of rice allergy in severe type of atopic dermatitis in Japan" 176 : 1037-, 1992

20 Orhan F, "A case of isolated rice allergy" 58 : 4567-, 2003

21 Hong CS, "A case of bronchial asthma induced by rice-bran" 7 : 236-242, 1987