BCAA 섭취가 지구성 운동 시 피로물질, 근 손상물질 및 에너지 대사물질에 미치는 영향

다국어 초록 (Multilingual Abstract)

The increase rate of utilization of branched-chain amino acids(BCAA) by muscle is reduced to its plasma concentration during prolonged exercise leading to glycogen. BCAA supplementation would reduce the serum activities of intramuscular enzymes associated with muscle damage. To examine the effects of BCAA administration on fatigue substances(serotonin, ammonia and lactate), muscle damage substances(CK and LDH) and energy metabolism substances (FFA and glucose) after endurance exercise.
Subjects(n=26, college-aged males) were randomly divided into an experimental(n=13, EXP) and a placebo(n=13, CON) group. Subjects both EXP and CON performed a bout of cycle training(70% VO2max intensity) to exhaustion. Subject in the EXP were administrated BCAA(78ml/kg&#8228;w) prior to the bout of cycle exercise. Fatigue substances, muscle damage substances and energy metabolism substances were measured before administration, 10 min before exercise, 30 min into exercise, post exercise, and recovery 30 min. Data were analyzed by two-way repeated measure ANCOVA, correlation and stepwise regression with statistical significance was set at p<0.05.
The following results were obtained from this study;
1. In the change of fatigue substances :
Serotonin in the EXP tended to decreased at the 10 min before exercise, 30 min into exercise, post exercise, and recovery 30 min. Serotonin in the CON was significantly greater than the EXP at the10 min before exercise and recovery 30. Ammonia in the EXP was increased at the 10 min before exercise, 30 min into exercise, and post exercise, but significantly decreased at the recovery 30min(p<0.05). Ammonia in the CON was significantly lower than the EXP at the 10 min before exercise, 30 min into exercise, and post exercise(p<0.05). Lactate in the EXP was significantly increased at the 30 min into exercise and significantly decreased at the post exercise and recovery 30 min. Lactate in the CON was significantly lower than the EXP at the post exercise(p<0.05).

2. In the change of muscle damage substances :
CK in the EXP was decreased at the 10 min before exercise and increased at the 30 min into exercise and then decreased at the post exercise and recovery 30 min. CK in the CON was greater than the EXP. LDH in the EXP was decreased at the 10 min before exercise and increased at the 30 min into exercise and then decreased at the post exercise and recovery 30 min. LDH in the CON was higher than the EXP.

3. In the change of energy metabolism substances :
Glucose in the EXP tended to decrease at the 10 min before exercise, 30 min into exercise, post exercise and recovery 30 min. Glucose in the CON was significantly greater than the EXP at the recovery 30 min(p<.05). FFA in both EXP and CON was increased at the post exercise and recovery 30 min. % increase for FFA in the EXP was greater than the CON at the post exercise and recovery 30 min.

4. The relationship of the fatigue substances, muscle damage substances and energy metabolism substances after endurance exercise indicated strongly a positive relationship between LDH and ammonia and a negative relationship between LDH and FFA in the EXP. Also, there were a strong negative relationship between glucose and FFA and a positive relationship between glucose and serotonin in the EXP. There was a strong positive relationship between CK and LDH and a strong negative relationship between FFA and glucose in the CON.

5. In the analyzing of the effects of variances that affect fatigue substances, muscle damage substances and energy metabolism substances after endurance exercise showed tendencies as :
In the EXP, the higher concentration of glucose and lower concentration of serotonin have influences on CK. The higher concentration of ammonia and lower concentration of serotonin and FFA have effects on LDH. The lower concentration of FFA and high concentration of serotonin and CK affect glucose. The lower concentration of glucose and LDH has effects on FFA. Also, the higher concentration of glucose and ammonia and low concentration of LDH and lactate have influences on serotonin. The higher concentration of LDH and serotonin affects ammonia.
In the CON, the higher concentration of LDH & FFA has effects on CK. The lower concentration of FFA and higher concentration CK affect LDH. The lower concentration of FFA and higher concentration serotonin has influences on glucose. The lower concentration of glucose and higher concentration of serotonin have effects on FFA.

These results indicate that supplementary BCAA decreased serum concentrations of the intramuscular enzymes as CK and LDH following exhaustive exercise. This observation suggests that BCAA supplementation may reduce the muscle damage associated with endurance exercise.

목차 (Table of Contents)

• Ⅰ. 서 론 1
• 1. 연구의 필요성 1
• 2. 연구의 목적 4
• 3. 연구 가설 4
• 4. 연구의 제한점 5
• Ⅱ. 이론적 배경 6
• 1. 운동과 BCAA 6
• 2. 운동과 피로물질 11
• 3. 운동과 근 손상물질 18
• 4. 운동과 에너지 대사물질 21
• Ⅲ. 연구방법 24
• 1. 연구대상 24
• 2. 실험설계 24
• 3. 실험절차 및 방법 25
• 4. 분석항목 및 방법 28
• 5. 자료처리 29
• Ⅳ. 연구결과 31
• 1. 지구성 운동 시 피로물질, 근 손상 물질 및 에너지 대사물질의 변화 31
• 2. 피로물질, 근 손상 물질 그리고 에너지 대사물질의 상관분석 37
• 3. 피로물질, 근 손상 물질 그리고 에너지 대사물질에 대한 다중회귀분석 38
• Ⅴ. 논 의 45
• 1. 운동과 피로물질 45
• 2. 운동과 근 손상 물질 53
• 3. 운동과 에너지 대사물질 56
• Ⅴ. 결 론 62
• 참고문헌 65
• Abstract 84