忠淸 地域의 타액선 腫瘍에 對한 組織化學的 硏究 = Histochemical Study of Salivary Gland Tumors in the Chungcheong Area

다국어 초록 (Multilingual Abstract)

For studies on the salivary gland tumors in Chungcheong areas, the specimens were collected at the department of pathology, Chungnam National University School of Medicine from January 1978 to December 1982, and analyzed to classify an assortment of salivary gland tumors on clinical or histological basis and performed histochemical studies using various special stains such as PAS, PAS after diastase digestion, Alucian blue, Toluidine blue and Masson trichrome stains.
The results were as follows:
1. Out of 73 cases, 60 cases(82.3%) occurred at the major salivary glands, and 60 cases (82.3%) were benign.
2. Of these major salivary gland tumors 10 cases(16.7%) were malignant while 3 cases (23.1%) of minor salivary glands were malignant.
3. Mucoid material found in the ductal lumen of pleomorphic adenoma, mucoepidermoid tumor and adenoid cystic carcinoma was PAS positive and also diastase resistant PAS positive. Material in the pseudocystic spaces of adenoid cystic carcinoma was strongly alucian blue positive, toluidine blue positive, and metachromatic.
4. Mucoid material in the stromal portions of pleomorphic adenoma, adenoid cystic carcino and mucoepidermoid tumor was alucian blue positive, toluidine blue positive and metachromatic.
5. Mucoid material in the glandular or ductal lumens of Warthin's tumor was PAS positive and not metachromatic with toluidine blue.
6. Results of the present study indicated that pleomorphic adenoma and adenoid cystic carcinoma were thought to originated from myoepithelial cells.
The mucoepidermoid tumor were thought to originate from large secretory ducts, and the acing cell tumors were derived from acinar cells.