가상경계기법을 통한 협착된 미세혈관에서 적혈구 분포의 수치 해석

다국어 초록 (Multilingual Abstract)

In order to investigate the distribution of red blood cells in a stenosed microvessel, three-dimensional blood flow simulations are conducted using immersed boundary methods. To treat deformable structures like blood cells, a continuous-forcing immersed boundary method is employed. Also, a ghost-cell immersed boundary method is employed to treat rigid and complex structures like a stenosed vessel. In the present study, two immersed boundary methods are integrated into a single computational framework by treating each structure separately. The present framework is validated through the simulation of blood flow in a straight microvessel compared with related previous studies. Present simulations of blood flow in a stenosed microvessel reveal that distribution of RBCs passing the stenosis is changed uniformly and the cell-free layer has significant spatial variation across the stenosis, which might induce the change of wall shear stress and flow resistance.

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