N/A
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https://www.riss.kr/link?id=A3262309
1999
-
500
SCOPUS,KCI등재,SCIE
학술저널
59-63(5쪽)
0
상세조회0
다운로드다국어 초록 (Multilingual Abstract)
Background: Contraction of anal sphincter muscle produces severe pain in perianal surgery post- operatively. Recent reports have indicated that effective and prolonged pain relief can be obtained by the injection of small doses of morphine into the su...
Background: Contraction of anal sphincter muscle produces severe pain in perianal surgery post- operatively. Recent reports have indicated that effective and prolonged pain relief can be obtained by the injection of small doses of morphine into the subarachnoid space. We attempted to use this technique for perianal surgery and investigated postoperative pain control and its side effects.
Methods: Forty five patients scheduled for hemorrhoidectomy and anal fistulectomy were studied to determine the minimal effective dose of intrathecal morphine for postoperative analgesia. In order to control the pain, 7 mg of 0.5% hyperbaric bupivacaine with 0.05 mg (group I), 0.1 mg (group II) and 0.15 mg (group lII) of morphine hydrochloride was injected with a 25 gauge spinal needle into the subarachnoid space. We estimated the duration of analgesia until the pain score attained to above 3 in 10 cm VAS (visual analogue scale) and incidence of itching, nausea and vomiting by percentage, headache, backpain and respiratory depression by positive and negative. We also checked the time of self-voiding.
Results: The mean time of analgesia was 10.3+1.54, 19.7+2.22 and 20.3+2.29 hours in group I, II and III respectively. Urinary retention of group I, II and III after block persisted for an average of 20.3+2.31, 21.2+2.51 and 23.3+ 3.74 hours. Nausea and vomiting were observed 33%, 53%, 67% and itching was observed 53%, 67%, 80% in group I, II and III respectively and respiratory depression did not occur in all groups.
Conclusions: It is not necessary to use more than O. 1mg of intrathecal morphine in perianal surgery because analgesia is not prolonged and side effects are increased.
흰쥐에서 척수강내로 투여한 AMPA 수용체 길항제, ACEA 2085 의 항통각과민 효과
신경결찰로 인한 이질토에서 Metabotrophic Glutamate 5형 수용체의 변화에 대한 연구
복식전자궁적출술에서 술전 저용량 국수마취제와 Morphine을 이용한 경막외차단이 술후통증, 혈장 Cortisol, 혈당에 미치는 영향