TP-33 : Thematic Poster ; Absolute Eosinophils Count as a Marker of Mortality in Patients Admitted to Intensive Care Unit = TP-33 : Thematic Poster ; Absolute Eosinophils Count as a Marker of Mortality in Patients Admitted to Intensive Care Unit

다국어 초록 (Multilingual Abstract)

Background: Inflammatory markers may have a role in predicting severity of illness of intensive care unit (ICU) patients. The reduction in the number of eosinophils may be linked to the action of inflammatory cytokine. The aim of the study was to evaluate the absolute eosinophils count as a marker of mortality in patients admitted to intensive care unit. Methods: We retrospectively evaluated 28-day mortality and identified risk factors for 28-day mortality in consecutive patients admitted to the ICU. Daily eosinophils count and C-reactive protein (CRP) in all patients was analyzed. Results: A total of 122 patients were included in the study. The median age was 69.2 years. Overall 28-day mortality was 27.8% (n=34). At discharge, the significant differences were found in eosinophils count collected between survivors and nonsurvivors (260 vs 55, p＜0.05). When the eosinophils counts at discharge was assessed, an area under the curve (AUC) of 0.41 (95% confidence interval, 0.30-0.51 was observed. However, CRP at discharge showed an AUC of 0.78 (95% confidence interval, 0.69-0.86). Conclusion: Eosinophils count were lower in nonsurvivors admitted to ICU, but its clinical usefulness seems limited in comparison with CRP.Background: Inflammatory markers may have a role in predicting severity of illness of intensive care unit (ICU) patients. The reduction in the number of eosinophils may be linked to the action of inflammatory cytokine. The aim of the study was to evaluate the absolute eosinophils count as a marker of mortality in patients admitted to intensive care unit. Methods: We retrospectively evaluated 28-day mortality and identified risk factors for 28-day mortality in consecutive patients admitted to the ICU. Daily eosinophils count and C-reactive protein (CRP) in all patients was analyzed. Results: A total of 122 patients were included in the study. The median age was 69.2 years. Overall 28-day mortality was 27.8% (n=34). At discharge, the significant differences were found in eosinophils count collected between survivors and nonsurvivors (260 vs 55, p＜0.05). When the eosinophils counts at discharge was assessed, an area under the curve (AUC) of 0.41 (95% confidence interval, 0.30-0.51 was observed. However, CRP at discharge showed an AUC of 0.78 (95% confidence interval, 0.69-0.86). Conclusion: Eosinophils count were lower in nonsurvivors admitted to ICU, but its clinical usefulness seems limited in comparison with CRP.