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      KCI등재후보

      방사선치료 후 연하장애의 관리와 약물치료 = Medical Management for Radiation-induced Dysphagia

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      https://www.riss.kr/link?id=A105480652

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      다국어 초록 (Multilingual Abstract)

      Dysphagia after radiotherapy for head and neck cancer is a common problem that affects the nutritional status and quality of life of patients. In particular, although radiation-induced dysphagia associated with late fibroatrophy is often progressive a...

      Dysphagia after radiotherapy for head and neck cancer is a common problem that affects the nutritional status and quality of life of patients. In particular, although radiation-induced dysphagia associated with late fibroatrophy is often progressive and intractable, there have been only few studies on the therapeutic options, and preventive efforts are not performed well in clinics. This review summarizes the management of radiation-induced dysphagia and suggests possible medical treatments based on the current evidence and reported pathophysiologic mechanisms.

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      참고문헌 (Reference)

      1 권찬혁, "Validity and Reliability of the Korean Version of the MD Anderson Dysphagia Inventory for Head and Neck Cancer Patients" 대한재활의학회 37 (37): 479-487, 2013

      2 Patel V, "Use of pentoxifylline and tocopherol in radiation-induced fibrosis and fibroatrophy" 55 : 235-241, 2017

      3 Dijkstra PU, "Trismus in head and neck oncology: a systematic review" 40 : 879-889, 2004

      4 Delanian S, "Significant clinical improvement in radiation-induced lumbosacral polyradiculopathy by a treatment combining pentoxifylline, tocopherol, and clodronate (Pentoclo)" 275 : 164-166, 2008

      5 Delanian S, "Randomized, placebo-controlled trial of combined pentoxifylline and tocopherol for regression of superficial radiation-induced fibrosis" 21 : 2545-2550, 2003

      6 Kotz T, "Prophylactic swallowing exercises in patients with head and neck cancer undergoing chemoradiation: a randomized trial" 138 : 376-382, 2012

      7 Messing BP, "Prophylactic Swallow Therapy for Patients with Head and Neck Cancer Undergoing Chemoradiotherapy: A Randomized Trial" 32 : 487-500, 2017

      8 Kulbersh BD, "Pretreatment, preoperative swallowing exercises may improve dysphagia quality of life" 116 : 883-886, 2006

      9 Carroll WR, "Pretreatment swallowing exercises improve swallow function after chemoradiation" 118 : 39-43, 2008

      10 Szczesniak MM, "Persistent dysphagia after head and neck radiotherapy: a common and under-reported complication with significant effect on non-cancer-related mortality" 26 : 697-703, 2014

      1 권찬혁, "Validity and Reliability of the Korean Version of the MD Anderson Dysphagia Inventory for Head and Neck Cancer Patients" 대한재활의학회 37 (37): 479-487, 2013

      2 Patel V, "Use of pentoxifylline and tocopherol in radiation-induced fibrosis and fibroatrophy" 55 : 235-241, 2017

      3 Dijkstra PU, "Trismus in head and neck oncology: a systematic review" 40 : 879-889, 2004

      4 Delanian S, "Significant clinical improvement in radiation-induced lumbosacral polyradiculopathy by a treatment combining pentoxifylline, tocopherol, and clodronate (Pentoclo)" 275 : 164-166, 2008

      5 Delanian S, "Randomized, placebo-controlled trial of combined pentoxifylline and tocopherol for regression of superficial radiation-induced fibrosis" 21 : 2545-2550, 2003

      6 Kotz T, "Prophylactic swallowing exercises in patients with head and neck cancer undergoing chemoradiation: a randomized trial" 138 : 376-382, 2012

      7 Messing BP, "Prophylactic Swallow Therapy for Patients with Head and Neck Cancer Undergoing Chemoradiotherapy: A Randomized Trial" 32 : 487-500, 2017

      8 Kulbersh BD, "Pretreatment, preoperative swallowing exercises may improve dysphagia quality of life" 116 : 883-886, 2006

      9 Carroll WR, "Pretreatment swallowing exercises improve swallow function after chemoradiation" 118 : 39-43, 2008

      10 Szczesniak MM, "Persistent dysphagia after head and neck radiotherapy: a common and under-reported complication with significant effect on non-cancer-related mortality" 26 : 697-703, 2014

      11 Davies AN, "Parasympathomimetic drugs for the treatment of salivary gland dysfunction due to radiotherapy" 2015

      12 Starmer HM, "One-Year Swallowing Outcomes in Patients Treated with Prophylactic Gabapentin During Radiation-Based Treatment for Oropharyngeal Cancer" 32 : 437-442, 2017

      13 Hutcheson KA, "Late dysphagia after radiotherapy-based treatment of head and neck cancer" 118 : 5793-5799, 2012

      14 Mortensen HR, "Late dysphagia after IMRT for head and neck cancer and correlation with dose-volume parameters" 107 : 288-294, 2013

      15 Delanian S, "Kinetics of response to long-term treatment combining pentoxifylline and tocopherol in patients with superficial radiation- induced fibrosis" 23 : 8570-8579, 2005

      16 Machtay M, "Factors associated with severe late toxicity after concurrent chemoradiation for locally advanced head and neck cancer: an RTOG analysis" 26 : 3582-3589, 2008

      17 Starmer HM, "Effect of gabapentin on swallowing during and after chemoradiation for oropharyngeal squamous cell cancer" 29 : 396-402, 2014

      18 Schindler A, "Dysphagia in head and neck cancer patients treated with radiotherapy and systemic therapies: Literature review and consensus" 96 : 372-384, 2015

      19 Eisbruch A, "Dysphagia and aspiration after chemoradiotherapy for head-and-neck cancer: which anatomic structures are affected and can they be spared by IMRT?" 60 : 1425-1439, 2004

      20 Servagi-Vernat S, "Dysphagia after radiotherapy: state of the art and prevention" 132 : 25-29, 2015

      21 Popovtzer A, "Anatomical changes in the pharyngeal constrictors after chemo-irradiation of head and neck cancer and their dose-effect relationships: MRI-based study" 93 : 510-515, 2009

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