Amphetamine and phenethylamine derivatives, methamphetamine, ephedrine and norephedrine react on heating with 7-chloro-4-nitrobenzo-2, 1, 3, -oxadiazole (NBD-CI) in alkaline methanolic solution to from highly fluorescent NBD-amine derivatives.
The th...
Amphetamine and phenethylamine derivatives, methamphetamine, ephedrine and norephedrine react on heating with 7-chloro-4-nitrobenzo-2, 1, 3, -oxadiazole (NBD-CI) in alkaline methanolic solution to from highly fluorescent NBD-amine derivatives.
The thin-layer chromatographic identification method and fluorometric determination of amphetamine and phenethiylamine derivatives are presented.
Reaction conditions are also described with solvent effect on maximum excitation and emision wavelengths and fluorscence intensity of NBD-amine derivatives.