Metal ion-complexed zwitterionic polyurethane additives for synergistically anti-bacterial polymeric surface = Metal ion-complexed zwitterionic polyurethane additives for synergistically anti-bacterial polymeric surface

다국어 초록 (Multilingual Abstract)

Although polyurethane (PU) based materials have been commonly used for biomedical devices due to their biocompatibility and mechanical properties, thrombosis and infection occurrence is still major problems. To prevent these, zwitterion groups have emerged as new generation of anti-fouling materials to inhibit protein adsorption and adhesion of platelet. In addition, some metal ions are known to their anti-microbial properties. Herein, we designed a series of metal ion-complexed zwitterionic polyurethane (m-zPU) additives to confer non-fouling and -microbial properties to polyvinyl chloride (PVC). Consequently, it is demonstrated that m-zPU additives significantly lowered protein adsorption and enlarged the zone of bacterial inhibition than pure PVC.