규칙적인 운동이 sarcopenic 비만여성고령자의 심혈관질환 위험인자에 미치는 영향

국문 초록 (Abstract)

고령기의 생활을 위협하는 obesity 여성고령자를 대상으로 sarcopenia 동반에 따른 CVD 위험의 가중성과 16 주간의 운동중재가 CVD 위험인자에 미치는 변화를 알아보고자 한다. 또한, 이러한 운동효과를 검증하여 obesity 여성 고령자에게 obesity와 sarcopenia에 대한 운동의 중요성을 부각시켜 삶의 질 향상에 도움을 주기 위한 연구이다. 비만 여성고령자를 sarcopenia 동반유무에 따라 sarcopenic obesity group(SOG)과 non-sarcopenic obesity group(NOG)으로 나 누어 16주간, 주 3회, 50-60분간 복합운동 실시 후 심혈관질환 위험인자에 미치는 영향을 분석하여 다음과 같은 결론 을 얻었다. 운동 전 두 그룹간 CVD 위험인자 비교에서는 비만 여성고령자에게 sarcopenia가 동반될 경우 CVD 위험 이 가중되지 않았으며, sarcopenic obesity 여성고령자가 non-sarcopenic obesity 여성고령자보다 HDL-C는 높게, TG는 더 낮게 나타났다. 운동중재 후에는 혈청지질에서 sarcopenic obesity 여성고령자의 경우 TC, TG는 감소하였고, HDL-C, LDL-C은 차이가 없었다. non-sarcopenic obesity 여성고령자의 경우 TC, TG, LDL-C는 감소하였으며, HDL-C 증가하였다. 따라서, sarcopenia와 CVD 위험인자와의 낮은 관련성을 확인할 수 있었으며, sarcopenic obesity 여성고령 자가 non-sarcopenic obesity 여성고령자에 비해 HDL-C, LDL-C, BP, right baPWV에서 운동효과가 더디다는 것을 발견할 수 있었다.

다국어 초록 (Multilingual Abstract)

The purpose of this study was to analyze the effects of combined exercise on body composition and cardiovascular disease risk factors in sarcopenic obesity elderly women. The subjects for the study were 21 obesity elderly women over 65 years old . They were divided into two groups, the sarcopenic obesity group(n=9) and non-sarcopenic obesity group(n=12). The variables of body composition and CVD risk factors were measured in all the subjects before and after 16-week combined exercise. The findings of this study were as follows; In the sarcopenic obesity elderly women significantly decreased total cholesterol(TC), triglyceride(TG), and left baPWV. The non-sarcopenic obesity elderly women significantly decreased total cholesterol(TC), triglyceride(TG), low density lipoprotein-cholesterol (LDL-C), and left baPWV, but significantly increased high density lipoprotein-cholesterol(HDL-C). The most important finding in this study was that sarcopenic obesity elderly women showed delayed effects of a 16-week combined exercise on HDL, LDL-C, BP, and right baPWV compared to the non-sarcopenic obesity elderly women.

참고문헌 (Reference)

1 김남정, "장기간의 시니어 신체리듬 운동프로그램이 폐경기 비만 노인여성의 신체구성과 대사증후군 위험 인자에 미치는 영향" 한국발육발달학회 17 (17): 127-131, 2009

2 이계영, "장기간 탄성밴드 운동이 비만 노인 여성의 신체구성과 혈중지질에 미치는 영향" 한국스포츠리서치 18 (18): 607-616, 2007

3 김명수, "운동 프로그램에 따른 비만 노인여성의 혈중지질, 렙틴 및 코티졸 변화" 한국사회체육학회 (36) : 663-671, 2009

4 김재희, "비만 노인 여성에서 저열량식과 근력운동의 병행이 근내지방과 혈중지질에 미치는 영향" 한국운동영양학회 13 (13): 9-14, 2009

5 박상갑, "복합운동프로그램이 Sarcopenia 여성노인을 위한 건강체력과 항노화호르몬 및 근감소증예방에 미치는 영향" 한국사회체육학회 (40) : 435-442, 2010

6 소위영, "미용덤벨 운동이 노인의 근감소증 예방을 위한 신체조성, 체력 및 혈중지질에 미치는 영향" 한국노년학회 29 (29): 837-850, 2009

7 박혜진, "모던댄스운동이 노인여성의 혈압 및 심혈관 반응에 미치는 영향" 한국사회체육학회 (37) : 1255-1264, 2009

8 이승범, "단전호흡이 본태성 고혈압 노인의 혈압 및 혈압조절 호르몬에 미치는 영향" 한국사회체육학회 20 (20): 1307-1315, 2003

9 Rush, J. W., "Vascular biology of angiotensin and the impact of physical activity" 33 : 162-172, 2008

10 Thijessen, D. H., "Vascular adaptations to 8-week cycling training in older men" 190 (190): 221-228, 2007

11 Yamashina, A., "Validity, reproducibility, and clinical significance of noninvasive brachial-ankle pulse wave velocity measurement" 25 (25): 359-364, 2002

12 Sarwar, N., "Triglycerides and the risk of coronary heart disease: 10,158 incident cases among 262,525 participants in 29 western prospective studies" 115 : 450-458, 2007

13 Dominguez, L. J., "The cardiometabolic syndrome and sarcopenic obesity in older persons" 2 (2): 183-189, 2007

14 Lim, K. I., "The association between the ratio of visceral fat to thigh muscle area and metabolic syndrome: the Korean Sarcopenic Obesity Study (KSOS)" BLACKWELL PUBLISHING 73 : 588-594, 201011

15 Stephen, W. C., "Sarcopenic-obesity and cardiovascular disease risk in the elderly" 13 (13): 460-466, 2009

16 Roubenoff, R., "Sarcopenic obesity: the confluence of two epidemics" 12 (12): 887-888, 2004

17 Zamboni, M., "Sarcopenic obesity: a new category of obesity in the elderly" 18 (18): 388-395, 2008

18 Zamboni, M., "Sarcopenic obesity: a new category of obesity in the elderly" 18 (18): 388-395, 2008

19 Baumgartner, R. N., "Sarcopenic obesity predicts instrumental activities of daily living disability in the elderly" 12 (12): 1995-2004, 2004

20 Schrager, M. A., "Sarcopenic obesity and inflammation in the InCHIANTI study" 102 (102): 919-925, 2007

21 Taaffe, D. R., "Sarcopenia: Exercise as a treatment strategy" 35 (35): 130-133, 2006

22 Newman, A. B., "Sarcopenia: Alternative definitions and associations with lower extremity function" 51 (51): 1602-1609, 2003

23 Greenlund, L. J., "Sarcopenia-consequences, mechanisms, and potential therapies" 124 : 287-299, 2003

24 Braith, R. W., "Resistance exercise: training adaptations and developing a safe exercise prescription" 13 (13): 69-79, 2008

25 Little, J. P., "Resistance exercise and nutrition to counteract muscle wasting" 34 (34): 817-828, 2009

26 Dinenno, F. A., "Regular endurance exercise induces expansive arterial remodelling in the trained limbs of healthy men" 534 : 287-295, 2001

27 Snijder, M. B., "Regional body composition as a determinant of arterial stiffness in the elderly: The Hoorn Study" 22 (22): 2339-2347, 2004

28 Kozakova, M, "RISC Investigators, Habitual physical activity and vascular aging in a young to middle-age population at low cardiovascular risk" 38 (38): 2549-2555, 2007

29 Kim T. N., "Prevalence of sarcopenia and sarcopenic obesity in Korean adults: the Korean sarcopenic obesity study" NATURE PUBLISHING GROUP 33 (33): 885-892, 200908

30 Iannuzzi, S. M., "Prevalence of Sarcopenia and predictors of skeletal muscle mass in healthy, older men and women" 57 (57): 772-777, 2002

31 Taylor, A. W., "Physiology of exercise and health aging" Human kinetics 2008

32 Korean Society of Exercise Physiology, "Physiology of Exercise" Hanmibook 2011

33 Korean Association of Certified Exercise Professionals, "Physiology of Exercise" Hanmibook 2007

34 Poirier, P., "Obesity and Cardiovascular Disease: Pathophysiology, Evaluation, and Effect of Weight Loss -An Update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease From the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism-" 113 : 898-918, 2006

35 LeMura, L. M., "Lipid and lipoprotein profiles, cardiovascular fitness, body composition, and diet during and after resistance, aerobic and combination training in young women" 82 : 451-458, 2000

36 Haywood, K. M., "Life span motor development. - 5th ed" Human kinetics 2009

37 Ryan, A. S., "Insulin resistance with aging: effects of diet and exercise" 30 (30): 327-346, 2000

38 Cornelissen, V. A., "Influence of exercise at lower and higher intensity on blood pressure and cardiovascular risk factors at older age" 27 (27): 753-762, 2009

39 Benetos, A., "Influence of age, risk factors, and cardiovascular and renal disease on arterial stiffness: clinical applications" 15 (15): 1101-1108, 2002

40 Kallinen, M., "Improving cardiovascular fitness by strength or endurance training in women aged 76-78 years. A population-based, randomized controlled trial" 31 : 247-254, 2002

41 Mizuguchi, Y., "Impact of statin therapy on left ventricular function and carotid arterial stiffness in patients with hypercholesterolemia" 72 (72): 538-544, 2008

42 Tanaka, H., "Habitual exercise for the elderly" 32 (32): S57-S65, 2009

43 Ferrari, C. K., "Functional foods and physical activities in health promotion of aging people" 58 (58): 327-339, 2007

44 O’Leary, V. B., "Exercise-induced reversal of insulin resistance in obese elderly is associated with reduced visceral fat" 100 (100): 1584-1589, 2006

45 Baumgartner, R. N., "Epidemiology of sarcopenia among the elderly in New Mexico" 147 (147): 755-763, 1998

46 Rosenberg, I. H., "Epidemiologic and methodologic problems in determining nutritional status of older persons" 50 (50): 1121-1235, 1989

47 Halverstadt, A., "Endurance exercise training raises high-density lipoprotein cholesterol and lowers small lowers small low-density lipoprotein and very low-density lipoprotein independent of body fat phenotypes in older men and women" 56 (56): 444-450, 2007

48 Benetos, A., "Effects of lean and fat mass on bone mineral density and arterial stiffness in elderly men" 20 (20): 1385-1391, 2009

49 Hayashi, K., "Effects of aerobic exercise training on the stiffness of central and peripheral arteries in middle-aged sedentary men" 55 (55): 235-239, 2005

50 Jang, J. H., "Effects of Long Term Combined Exercise Program on Body Composition and Rheumatiod arthritis inflammation factors in Sarcopenic Obesity Elderly Women" 251-, 2010

51 Kim, Y. S., "Effects of Isokinetic Exercise Prescrpition on the Improvement of Thigh Muscle Function and Blood Flow Velocity after Knee Joint Postoperative" 40 (40): 448-461, 2001

52 Aubertin-Leheudre, M., "Effect of sarcopenia on cardiovascular disease risk factors in obese postmenopausal women" 14 (14): 2277-2281, 2006

53 Edwards, D. G., "Effect of exercise training on central aortic pressure wave reflection in coronary artery disease" 17 (17): 540-543, 2004

54 Rolland, Y., "Difficulties with physical function associated with obesity, sarcopenia, and sarcopenic-obesity in community-dwelling elderly women: the EPIDOS Study" 89 (89): 1895-1900, 2009

55 Mitchell, G. F., "Changes in arterial stiffness and wave reflection with advencing age in healthy men and women: The Framingham Heart Study" 43 : 1249-1245, 2004

56 Helen, O., "Cardiovascular aging and heart failure" 5 : 427-434, 2003

57 Borg, G., "Borg's Perceived Exertion and Pain Scales" Human Kinetics 1998

58 Edwards, D. G., "Augmentation index and systolic load are lower in competitive endurance athletes" 18 (18): 679-683, 2005

59 Yamada. S., "Associations between physical activity, peripheral atherosclerosis and bone status in healthy Japanese women" 188 (188): 196-202, 2006

60 Jurca, R., "Association of muscular strength with incidence of metabolic syndrome in men" 37 (37): 1849-1855, 2005

61 Amar, J., "Arterial stiffness and cardiovascularrisk factors in a population-based study" 19 (19): 381-387, 2001

62 Mitchell, G. F., "Aortic diameter, wall stiffness, and wave reflection in systolic hypertension" 51 (51): 105-111, 2008

63 Kelley, G. A., "Aerobic exercise and lipids and lipoproteins in women: a meta-analysis of randomized controlled trial" 13 (13): 1148-1164, 2004

64 ACSM, "ACSM's Resource for Guidelines for Exercise Testing and Prescription-8th Ed" Lippincott Williams & Wilkins 2010

65 Ministry of Health and Welfare, "2009 National Health Statistics; National Health and Nutrition Survey 4th 3 year(2009)" 2011

66 김상훈, "12주간의 순환운동이 노인비만여성의 비만, 체력 및 대사증후군 지표에 미치는 영향" 한국노년학회 29 (29): 823-835, 2009