단백질 서열과 이차 구조의 상호 정보 분석 = Analysis of Mutual Information Between a Protein Sequence and a Secondary Structure

다국어 초록 (Multilingual Abstract)

In order to predict the three-dimensional structure of a protein from its amino-acid sequence, it is important to analyze the correlation between the sequence and the structure and to extract from the sequence features that play a crucial role in determining the protein structure. In this work, by using mutual information, we analyzed the correlation between the protein sequence and the secondary structure, where the protein sequence was expressed in terms of a reduced set of amino acids corresponding to hydrophobic,hydrophilic, and neutral ones, and the secondary structure was classified into eight classes.

국문 초록 (Abstract)

단백질의 아미노산 서열로부터 단백질의 삼차원 구조를 예측하기위해서는 단백질의 서열과 구조 간의 상관관계를 파악하여, 단백질의구조를 결정하는데 중요한 역할을 하는 특징을 추출하는 것이 중요하다.
본 연구에서는 단백질을 이루는 아미노산을 친수성, 소수성, 중성의 세가지로 표현한 단백질 서열과, 여덟 가지로 분류되는 단백질의 이차구조와의 상관관계를 상호정보를 써서 분석하였다.

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