Bioorthogonal approach for functional peptides and proteins = Bioorthogonal approach for functional peptides and proteins

다국어 초록 (Multilingual Abstract)

A wide variety of different biomaterials are currently employed in medical applications throughout the world. Research towards the development of new biomaterials has traditionally focused on the preparation of functional materials capable of the simple adhesion of cells or the connection of tissues to metals and ceramics. There is a growing interest in the development of biomaterials involving the immobilization of growth factors, which would allow these artificial materials to regulate specific cellular functions, including the gene expression processes associated with cell growth and differentiation. In order to design growth factor proteins which can adhere these artificial materials, bioorthogonal approaches inspired by underwater adhesive proteins have recently been employed.