Does Platelet-rich Plasma Augmentation Following Hip Arthroscopy Improve Outcomes: A Systematic Review

다국어 초록 (Multilingual Abstract)

Platelet-rich plasma (PRP) has gathered widespread acceptance among orthopaedic surgeons because of its multimodal effects on tissue healing. Varying results have been reported when PRP injections are combined with hip arthroscopic surgery. To evaluate the influence of PRP on clinical outcomes following hip arthroscopy. We hypothesized that patients treated with PRP would have improved postoperative outcome scores. A search of the National Institute for Health and Care Excellence (NICE) healthcare database advanced search (HDAS) via Athens (PubMed, MEDLINE, CINAHL, EMBASE, and AMED databases) was conducted from their years of inception to May 2018 with the keywords: “Hip Arthroscopy” and “Platelet-Rich Plasma”. A quality assessment was performed based on the Cochrane risk of bias tool. Three studies were included for analysis; two of which had low risk of bias. The studies included 363 hips, of which 141 were randomised for PRP treatment. The mean age of all patients was 35 years and the follow-up ranged from 18.5 to 36 months. Authors used different PRP systems and preparations. Modified Harris hip score was reported in all three studies with two studies favouring the use of PRP. The use of PRP following hip arthroscopy did not lead to significantly improved postoperative pain or functional outcomes when compared to control groups in the studies included in this review.

참고문헌 (Reference)

1 McCarthy JC, "What factors influence long-term survivorship after hip arthroscopy?" 469 : 362-371, 2011

2 Sánchez M, "Ultrasound-guided platelet-rich plasma injections for the treatment of osteoarthritis of the hip" 51 : 144-150, 2012

3 Sengodan VC, "Treatment of partial rotator cuff tear with ultrasound-guided platelet-rich plasma" 7 : 32-, 2017

4 Kraeutler MJ, "The use of platelet-rich plasma to augment conservative and surgical treatment of hip and pelvic disorders" 6 : 410-419, 2016

5 Sun Y, "The regenerative effect of platelet-rich plasma on healing in large osteochondral defects" 34 : 589-597, 2010

6 Vavken P, "The potential for primary repair of the ACL" 19 : 44-49, 2011

7 LaFrance R, "The effect of platelet enriched plasma on clinical outcomes in patients with femoroacetabular impingement following arthroscopic labral repair and femoral neck osteoplasty" 2 : 158-163, 2015

8 Zhou Y, "The differential effects of leukocyte-containing and pure platelet-rich plasma(PRP)on tendon stem/progenitor cells-implications of PRP application for the clinical treatment of tendon injuries" 6 : 173-, 2015

9 Alsousou J, "The biology of platelet-rich plasma and its application in trauma and orthopaedic surgery : a review of the literature" 91 : 987-996, 2009

10 Higgins JP, "The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials" 343 : d5928-, 2011

11 Moher D, "Preferred reporting items for systematic reviews and metaanalyses:the PRISMA statement" 6 : e1000097-, 2009

12 Mei-Dan O, "Platelet-rich plasma or hyaluronate in the management of osteochondral lesions of the talus" 40 : 534-541, 2012

13 Rafols C, "Platelet-rich plasma augmentation of arthroscopic hip surgery for femoroacetabular impingement : a prospective study with 24-month follow-up" 31 : 1886-1892, 2015

14 Zayni R, "Platelet-rich plasma as a treatment for chronic patellar tendinopathy : comparison of a single versus two consecutive injections" 5 : 92-98, 2015

15 De Pascale MR, "Platelet derivatives in regenerative medicine : an update" 29 : 52-61, 2015

16 Dhillon MS, "PRP in OA knee-update, current confusions and future options" 3 : 27-, 2017

17 Yan R, "Intratendon delivery of leukocytepoor platelet-rich plasma improves healing compared with leukocyte-rich platelet-rich plasma in a rabbit achilles tendinopathy model" 45 : 1909-1920, 2017

18 Freeman CR, "Hip preservation surgery : surgical care for femoroacetabular impingement and the possibility of preventing hip osteoarthritis" 1 : 46-55, 2014

19 Higgins JPT, "Cochrane handbook for systematic reviews of interventions version 5.1.0"

20 Redmond JM, "Clinical results of hip arthroscopy for labral tears : a comparison between intraoperative platelet-rich plasma and bupivacaine injection" 31 : 445-453, 2015

21 Varshney A, "Autologous platelet-rich plasma versus corticosteroid in the management of elbow epicondylitis : a randomized study" 7 : 125-128, 2017

22 Randelli PS, "Autologous platelet rich plasma for arthroscopic rotator cuff repair" 30 : 1584-1589, 2008

23 Guadilla J, "Arthroscopic management and platelet-rich plasma therapy for avascular necrosis of the hip" 20 : 393-398, 2012