쇠미역사촌 추출물의 항산화 효과와 항균 효과 = Antioxidant and Anti-bacterial Effect of Costaria Costata (C. Agardh) Saunders Extracts

다국어 초록 (Multilingual Abstract)

This study investigated the effect of Costaria costata (C. Agardh) Saunders extracts on dermal cells. The total extract of C. Agardh Saunders was partitioned into the chloroform (CHCl3) and distilled water (DW) fractions. C. Agardh Saunders extracts did not show cytotoxicity on HaCaT human keratinocytes and B16F10 mouse melanoma cell lines at concentrations of 10 μg/mL, 20 μg/mL, and 40 μg/mL. Both the CHCl3 and DW extracts inhibited oxidative stress, and the effect was superior to glutathione, which was used as a positive control. Moreover, the DW extracts of C. Agardh Saunders inhibited melanin synthesis in the cells activated with α-melanocyte-stimulating hormone. The CHCl3 extracts of C. Agardh Saunders exhibited antibacterial effects toward Staphylococcus aureus, Staphylococcus epidermidis, and Pseudomonas aeruginosa. The CHCl3 fraction (Minimum Inhibitory Concentration, MIC: 0.5 mg/mL) of C.
Agardh Saunders extracts was effective in terms of antibacterial activity against S. aureus. The present study suggests that applications of C. Agardh Saunders extracts can be used in terms of novel cosmetic materials as well as antibacterial food preservatives.

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