목적: 토끼에서 스펙트럼영역 빛간섭단층촬영(spectral domain optical coherence tomography, SD-OCT)을 이용하여 시신경유두(optic nerve head, ONH)로부터 거리에 따른 망막 각 층의 두께를 측정하고 이를 통해...
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https://www.riss.kr/link?id=A107379556
2021
-
510
KCI등재,SCOPUS,ESCI
학술저널
354-361(8쪽)
0
0
상세조회0
다운로드국문 초록 (Abstract)
목적: 토끼에서 스펙트럼영역 빛간섭단층촬영(spectral domain optical coherence tomography, SD-OCT)을 이용하여 시신경유두(optic nerve head, ONH)로부터 거리에 따른 망막 각 층의 두께를 측정하고 이를 통해...
목적: 토끼에서 스펙트럼영역 빛간섭단층촬영(spectral domain optical coherence tomography, SD-OCT)을 이용하여 시신경유두(optic nerve head, ONH)로부터 거리에 따른 망막 각 층의 두께를 측정하고 이를 통해 망막 동물실험모델에서의 기본 자료를 얻고자 한다. 대상과 방법: 토끼 15마리의 우안에서 SD-OCT 영상을 얻은 후, ONH 테두리에서 시작하여 하방으로 1, 2, 3, 4 그리고 5 mm 위치에서 전체 망막층, 내망막층, 외망막층, 맥락막층, 신경절세포복합체층, 신경절세포층, 내핵층, 그리고 외핵층의 두께를 얻었으며, 측정 위치에 따른 각 층의 두께를 비교하였다. 결과: 총 망막두께(Pearson’s correlation coefficient [CC]=-0.778, p<0.05), 내망막층 두께(CC=-0.710, p<0.05), 외망막층 두께(CC=-0.495, p<0.05), 신경절세포복합체 두께(CC=-0.292, p<0.05), 신경절세포층 두께(CC=-0.284, p<0.05), 그리고 외핵층 두께(CC=-0.760, p<0.05)는 ONH에서 아래로 멀어질수록 감소하였다. 내핵층 두께도 ONH에서의 거리와 음의 상관관계를 보였으나 상관계수는 낮았다(CC=-0.263, p<0.05). 맥락막두께는 ONH에서 멀어질수록 증가하였다(CC=0.511, p<0.05). 결론: SD-OCT를 이용하여 ONH로부터 거리에 따른 토끼 망막두께를 분석하였다. 이 토끼 안저를 이해하는 데 도움이 될 것이며, 토끼 실험의 표준 자료로 사용할 수 있을 것이다.
다국어 초록 (Multilingual Abstract)
Purpose: We used spectral domain optical coherence tomography (SD-OCT) to assess the retinal and choroidal thicknesses of the rabbit, a commonly used animal model of ophthalmic disease. We report normative datasets. Methods: Semi-automated measurement...
Purpose: We used spectral domain optical coherence tomography (SD-OCT) to assess the retinal and choroidal thicknesses of the rabbit, a commonly used animal model of ophthalmic disease. We report normative datasets. Methods: Semi-automated measurements were made on 15 normal right eyes of New Zealand white rabbits. Total retinal, inner retinal layer, outer retinal layer, choroidal, ganglion cell layer, ganglion cell complex, inner nuclear layer, and outer nuclear layer thicknesses were measured at fixed distances (0, 1, 2, 3, 4, and 5 mm) below the optic nerve head. Results: Total retinal layer (Pearson’s correlation coefficient [CC] = -0.778, p < 0.05), inner retinal layer (CC = -0.710, p < 0.05), outer retinal layer (CC = -0.495, p < 0.05), ganglion cell complex (CC = -0.292, p < 0.05), ganglion cell layer (CC = -0.284, p < 0.05), and outer nuclear layer thicknesses (CC = -0.760, p < 0.05) decreased with the distance from the optic nerve head. Inner nuclear layer thickness correlated negatively with the distance from the optic nerve head, but the correlation coefficient was low (CC = -0.263, p < 0.05). Choroidal thickness increased with the distance from the optic nerve head (CC = 0.511, p < 0.05). Conclusions: Rabbit retinal thicknesses were measured and analyzed by the distance from the optic nerve head. The datasets will serve as standards when using rabbits.
참고문헌 (Reference)
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안장 위 수막종의 시신경 침범 환자에서 나타난자발적인 시력회복 1예
반복적인 전층각막이식실패 환자에서 데스메막박리 자동 각막내피층판이식술을 시행한 1예
앞허혈시신경병증 환자에서 뇌자기공명영상으로 확인한 측두동맥염
학술지 이력
연월일 | 이력구분 | 이력상세 | 등재구분 |
---|---|---|---|
2023 | 평가예정 | 해외DB학술지평가 신청대상 (해외등재 학술지 평가) | |
2020-01-01 | 평가 | 등재학술지 유지 (해외등재 학술지 평가) | |
2017-01-01 | 평가 | 등재학술지 유지 (계속평가) | |
2013-01-01 | 평가 | 등재 1차 FAIL (등재유지) | |
2010-01-01 | 평가 | 등재학술지 유지 (등재유지) | |
2007-01-01 | 평가 | 등재학술지 선정 (등재후보2차) | |
2006-01-01 | 평가 | 등재후보 1차 PASS (등재후보1차) | |
2005-01-01 | 평가 | 등재후보학술지 유지 (등재후보1차) | |
2003-01-01 | 평가 | 등재후보학술지 선정 (신규평가) |
학술지 인용정보
기준연도 | WOS-KCI 통합IF(2년) | KCIF(2년) | KCIF(3년) |
---|---|---|---|
2016 | 0.22 | 0.22 | 0.22 |
KCIF(4년) | KCIF(5년) | 중심성지수(3년) | 즉시성지수 |
0.23 | 0.23 | 0.366 | 0.02 |