인진쑥(Artemisia iwayomogi) 올리고당류(AIP1)의 기능성 탐색 = Functional activities of the oligosaccharide fraction AIP1 purified from Artemisia iwayomogi

다국어 초록 (Multilingual Abstract)

Objective: We examined the effects of the AIPI on the cell apoptosis, colonal and pathogenic microbial activities in vitro, and glycemic controls in vivo.
Methods and Materials: The oligosaccharide fraction AIPI was isolated and purified from Artemisia iwayomogi by the aqueous extraction and gel filtration chromatography.
Results: In the experiment of murine macrophage culture, the AIPI decreased the apoptotic cell death. In the mircrobiological experiments of the Bifidobacterium and Lactobacillus from the human intestine, the AIPI stimulated these colonal microbialactivities. However, the AIPI showed a strong inhibition against activities of the Listeria monocytogenes and Klebsiella pneumoniae in the experiments of the agar-diffusion and the estrase-FDA. In the animal experiment, the AIPI lowered the blood glucose curves of the glucose tolerance test in the diabetic rats.
Conclusion: It is concluded that the oligosaccharide fraction AIPI from the Artemisia lwayomogi may have several beneficial functions as an immune booster, colonal probiotics, antimicrobial agent, and glucose intolerance alleviatin-biohealth material.